AP2M1

Protein sy'n cael ei godio yn y corff dynol gan y genyn AP2M1 yw AP2M1 a elwir hefyd yn Adaptor related protein complex 2 mu 1 subunit ac AP-2 complex subunit mu (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q27.1.

AP2M1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1H6E, 2JKT, 2JKR, 2VGL, 2BP5
Dynodwyr
Cyfenwau	AP2M1, AP50, CLAPM1, mu2, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, MRD60
Dynodwyr allanol	OMIM: 601024 HomoloGene: 3000 GeneCards: AP2M1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipid binding • clathrin adaptor activity • transporter activity • transmembrane transporter binding • GO:0001948, GO:0016582 protein binding • signal sequence binding • low-density lipoprotein particle receptor binding Cydrannau o'r gell • extracellular exosome • lysosomal membrane • AP-2 adaptor complex • endocytic vesicle membrane • cytosol • bilen • endolysosome membrane • clathrin adaptor complex • clathrin-coated pit • clathrin-coated endocytic vesicle membrane • Cellbilen • clathrin-coated endocytic vesicle Prosesau biolegol • ephrin receptor signaling pathway • GO:0019049, GO:0030683 mitigation of host defenses by virus • clathrin-dependent endocytosis • negative regulation of protein localization to plasma membrane • antigen processing and presentation of exogenous peptide antigen via MHC class II • endocytosis • protein transport • vesicle-mediated transport • intracellular protein transport • Wnt signaling pathway, planar cell polarity pathway • microtubule-based movement • membrane organization • low-density lipoprotein particle receptor catabolic process • low-density lipoprotein particle clearance • GO:0015915 transport • vesicle budding from membrane • receptor internalization • regulation of vesicle size Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1173	n/a
Ensembl	ENSG00000161203	n/a
UniProt	Q96CW1	n/a
RefSeq (mRNA)	NM_004068 NM_001025205 NM_001311198	n/a
RefSeq (protein)	NP_001020376 NP_001298127 NP_004059	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AP2M1.

• mu2
• AP50
• CLAPM1

Llyfryddiaeth

• "Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly. ". PLoS Pathog. 2012. PMID 22916011.
• "Roles of AP-2 in clathrin-mediated endocytosis. ". PLoS One. 2010. PMID 20485680.
• "Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process. ". Mol Biol Cell. 2007. PMID 17108328.
• "Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments. ". Proc Natl Acad Sci U S A. 2005. PMID 15911768.
• "Endocytic clathrin-coated pit formation is independent of receptor internalization signal levels.". Mol Biol Cell. 1998. PMID 9571248.