APBA3

Protein sy'n cael ei godio yn y corff dynol gan y genyn APBA3 yw APBA3 a elwir hefyd yn Amyloid beta precursor protein binding family A member 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.3.

APBA3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2YT7, 2YT8
Dynodwyr
Cyfenwau	APBA3, MGC:15815, X11L2, mint3, amyloid beta precursor protein binding family A member 3
Dynodwyr allanol	OMIM: 604262 HomoloGene: 3591 GeneCards: APBA3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • enzyme binding • GO:0048551 enzyme inhibitor activity • amyloid-beta binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • perinuclear region of cytoplasm • Cellbilen • dendritic spine • synapse Prosesau biolegol • protein transport • GO:0048552 regulation of catalytic activity • GO:0048553 negative regulation of catalytic activity • in utero embryonic development • chemical synaptic transmission • regulation of gene expression Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9546	n/a
Ensembl	ENSG00000011132	n/a
UniProt	O96018	n/a
RefSeq (mRNA)	NM_004886	n/a
RefSeq (protein)	NP_004877	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APBA3.

• X11L2
• mint3
• MGC:15815

Llyfryddiaeth

• "Interaction of Mint3 with Furin regulates the localization of Furin in the trans-Golgi network. ". J Cell Sci. 2008. PMID 18544638.
• "Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network. ". Mol Biol Cell. 2008. PMID 17959829.
• "Amyloid precursor protein associates independently and collaboratively with PTB and PDZ domains of mint on vesicles and at cell membrane. ". Neuroscience. 2001. PMID 11440799.
• "Genomic organization of the human X11L2 gene (APBA3), a third member of the X11 protein family interacting with Alzheimer's beta-amyloid precursor protein. ". Neuroreport. 1999. PMID 10574372.
• "Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex.". J Biol Chem. 2013. PMID 23965993.