Yn 2012, effeithiodd canser yr ysgyfaint ar 1.8 miliwn o bobl ar draws y byd, gan arwain at 1.6 miliwn o farwolaethau.<ref name=WCR2014Chp5.1>{{cite book|title=World Cancer Report 2014|date=2014|publisher=World Health Organization|isbn=92-832-0429-8|pages=Chapter 5.1}}</ref> Hwn felly sy'n achosi'r fwyafnifer mwyaf o farwolaethau cysylltiedig â chanser ymysg dynion, a'r ailnifer fwyafmwyaf cyffredin ond un ymysg menywod, ar ôl [[canser y fron]].<ref name=WCR2014Epi>{{cite book|title=World Cancer Report 2014|date=2014|publisher=World Health Organization|isbn=92-832-0429-8|pages=Chapter 1.1}}</ref> Mae diagnosis yn fwyaf cyffredin ymhlith y rheini sy'n 70 mlyneddmlwydd oed a thosodd. Yr yr [[Unol Daleithiau America|Unol Daleithiau]], yn yr un flwyddyn, goroesodd 17.4% o ddioddefwyr oam leiaf pumbum mlynedd o leiaf wedi eu diagnosis,<ref name="SEER">{{cite web | title=Surveillance, Epidemiology and End Results Program | url=http://seer.cancer.gov/statfacts/html/lungb.html | website=National Cancer Institute | accessdate=5 Mar 2016 | deadurl=no | archiveurl=https://web.archive.org/web/20160304031945/http://seer.cancer.gov/statfacts/html/lungb.html | archivedate=4 March 2016 | df=dmy-all }}</ref> ond y mae'r cyfartaledd hwnnw dipyn yn is yn y byd datblygol.<ref name=Maj2009>{{cite book|last=Majumder|first=edited by Sadhan|title=Stem cells and cancer|year=2009|publisher=Springer|location=New York|isbn=978-0-387-89611-3|page=193|url=https://books.google.com/books?id=HaErOupWnO0C&pg=PA193|edition=Online-Ausg.|deadurl=no|archiveurl=https://web.archive.org/web/20151018040051/https://books.google.com/books?id=HaErOupWnO0C&pg=PA193|archivedate=18 October 2015|df=dmy-all}}</ref>
