EDF1

Protein sy'n cael ei godio yn y corff dynol gan y genyn EDF1 yw EDF1 a elwir hefyd yn Endothelial differentiation related factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q34.3.

EDF1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1X57
Dynodwyr
Cyfenwau	EDF1, EDF-1, MBF1, CFAP280, endothelial differentiation related factor 1
Dynodwyr allanol	OMIM: 605107 HomoloGene: 2809 GeneCards: EDF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0102674, GO:0102675 methyltransferase activity • sequence-specific DNA binding • DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001105 transcription coactivator activity • calmodulin binding • histone acetyltransferase activity • GO:0001948, GO:0016582 protein binding • RNA binding • TFIID-class transcription factor complex binding Cydrannau o'r gell • cytoplasm • transcription factor TFIID complex • intracellular anatomical structure • nucleolus • extracellular exosome • cnewyllyn cell • cytosol Prosesau biolegol • cell differentiation • GO:0009373 regulation of transcription, DNA-templated • transcription, DNA-templated • multicellular organism development • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • regulation of lipid metabolic process • endothelial cell differentiation • positive regulation of DNA binding Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8721	n/a
Ensembl	ENSG00000107223	n/a
UniProt	O60869	n/a
RefSeq (mRNA)	NM_153200 NM_001281297 NM_001281298 NM_001281299 NM_003792	n/a
RefSeq (protein)	NP_001268226 NP_001268227 NP_001268228 NP_003783 NP_694880	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EDF1.

• MBF1
• EDF-1
• CFAP280

Llyfryddiaeth

• "Identification of the core domain and the secondary structure of the transcriptional coactivator MBF1. ". Genes Cells. 1999. PMID 10469174.
• "EDF-1, a novel gene product down-regulated in human endothelial cell differentiation. ". J Biol Chem. 1998. PMID 9813014.
• "Human multiprotein bridging factor 1 and Calmodulin do not interact in vitro as confirmed by NMR spectroscopy and CaM-agarose affinity chromatography. ". Protein Expr Purif. 2011. PMID 21782027.
• "Characterization of the human EDF-1 minimal promoter: involvement of NFY and Sp1 in the regulation of basal transcription. ". Gene. 2006. PMID 16567061.
• "The dual role of endothelial differentiation-related factor-1 in the cytosol and nucleus: modulation by protein kinase A.". Cell Mol Life Sci. 2004. PMID 15112053.