EHD1

Protein sy'n cael ei godio yn y corff dynol gan y genyn EHD1 yw EHD1 a elwir hefyd yn EH domain containing 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q13.1.

EHD1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2JQ6, 2KFF, 2KFG, 2KFH, 2KSP
Dynodwyr
Cyfenwau	EHD1, H-PAST, HPAST1, PAST, PAST1, EH domain containing 1
Dynodwyr allanol	OMIM: 605888 HomoloGene: 81678 GeneCards: EHD1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • calcium ion binding • GTP binding • metal ion binding • GO:0001948, GO:0016582 protein binding • ATP binding • cadherin binding • identical protein binding Cydrannau o'r gell • endosome • cell projection • early endosome membrane • bilen • lipid droplet • Cellbilen • cilium • recycling endosome membrane • platelet dense tubular network membrane • ciliary membrane • ciliary pocket membrane • endosome membrane • extracellular exosome Prosesau biolegol • cellular response to nerve growth factor stimulus • endocytosis • low-density lipoprotein particle clearance • positive regulation of cholesterol storage • blood coagulation • positive regulation of myoblast fusion • cell projection organization • protein localization to cilium • positive regulation of endocytic recycling • cholesterol homeostasis • intracellular protein transport • protein homooligomerization • neuron projection development • protein transport • endocytic recycling • cilium assembly • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10938	n/a
Ensembl	ENSG00000110047	n/a
UniProt	Q9H4M9	n/a
RefSeq (mRNA)	NM_001282444 NM_001282445 NM_006795	n/a
RefSeq (protein)	NP_001269373 NP_001269374 NP_006786	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EHD1.

• PAST
• PAST1
• H-PAST
• HPAST1

Llyfryddiaeth

• "Structural insight into the interaction of proteins containing NPF, DPF, and GPF motifs with the C-terminal EH-domain of EHD1. ". Protein Sci. 2009. PMID 19798736.
• "Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling. ". Mol Biol Cell. 2009. PMID 19369419.
• "Mammalian Eps15 homology domain 1 promotes metastasis in non-small cell lung cancer by inducing epithelial-mesenchymal transition. ". Oncotarget. 2017. PMID 27531895.
• "EHD1 confers resistance to cisplatin in non-small cell lung cancer by regulating intracellular cisplatin concentrations. ". BMC Cancer. 2016. PMID 27411790.
• "Molecular dynamics simulation of the interactions between EHD1 EH domain and multiple peptides.". J Zhejiang Univ Sci B. 2015. PMID 26465136.