ELL

Protein sy'n cael ei godio yn y corff dynol gan y genyn ELL yw ELL a elwir hefyd yn Elongation factor for RNA polymerase II (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 19, band 19p13.11.

ELL
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DOA
Dynodwyr
Cyfenwau	ELL, C19orf17, ELL1, MEN, PPP1R68, elongation factor for RNA polymerase II
Dynodwyr allanol	OMIM: 600284 HomoloGene: 4762 GeneCards: ELL
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phosphatase binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • Cajal body • nuclear speck • histone locus body • nucleoplasm • transcription elongation factor complex • cnewyllyn cell Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • snRNA transcription by RNA polymerase III • negative regulation of phosphatase activity • transcription elongation from RNA polymerase II promoter • in utero embryonic development • transcription by RNA polymerase II • transcription, DNA-templated • positive regulation of DNA-templated transcription, elongation • positive regulation of transcription by RNA polymerase III • positive regulation of transcription elongation from RNA polymerase II promoter • snRNA transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8178	n/a
Ensembl	ENSG00000105656	n/a
UniProt	P55199	n/a
RefSeq (mRNA)	NM_006532	n/a
RefSeq (protein)	NP_006523	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ELL.

• MEN
• ELL1
• PPP1R68
• C19orf17

Llyfryddiaeth

• "ELL targets c-Myc for proteasomal degradation and suppresses tumour growth. ". Nat Commun. 2016. PMID 27009366.
• "ELL facilitates RNA polymerase II pause site entry and release. ". Nat Commun. 2012. PMID 22252557.
• "The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis. ". Mol Cell Biol. 2001. PMID 11463848.
• "Identification and purification of the Holo-ELL complex. Evidence for the presence of ELL-associated proteins that suppress the transcriptional inhibitory activity of ELL. ". J Biol Chem. 1998. PMID 9556611.
• "An RNA polymerase II elongation factor encoded by the human ELL gene.". Science. 1996. PMID 8596958.