ELMO1

Protein sy'n cael ei godio yn y corff dynol gan y genyn ELMO1 yw ELMO1 a elwir hefyd yn Engulfment and cell motility 1 ac Engulfment and cell motility protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p14.2-p14.1.

ELMO1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2RQR, 2VSZ, 3A98
Dynodwyr
Cyfenwau	ELMO1, CED-12, CED12, ELMO-1, engulfment and cell motility 1
Dynodwyr allanol	OMIM: 606420 HomoloGene: 56685 GeneCards: ELMO1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • guanyl-nucleotide exchange factor activity • SH3 domain binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytosol • cytoplasm • guanyl-nucleotide exchange factor complex • Cellbilen • bilen Prosesau biolegol • Fc-gamma receptor signaling pathway involved in phagocytosis • actin filament-based process • GO:0019049, GO:0030683 mitigation of host defenses by virus • phagocytosis, engulfment • vascular endothelial growth factor receptor signaling pathway • ffagocytosis • Rac protein signal transduction • cell migration • actin cytoskeleton organization • GO:0097285 apoptotic process • cell motility • regulation of molecular function Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9844	n/a
Ensembl	ENSG00000155849	n/a
UniProt	Q92556	n/a
RefSeq (mRNA)	NM_001039459 NM_001206480 NM_001206482 NM_014800 NM_130442	n/a
RefSeq (protein)	NP_001034548 NP_001193409 NP_001193411 NP_055615 NP_569709	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ELMO1.

• CED12
• CED-12
• ELMO-1

Llyfryddiaeth

• "The over-expression of cell migratory genes in alveolar rhabdomyosarcoma could contribute to metastatic spread. ". Clin Exp Metastasis. 2012. PMID 22415709.
• "An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. ". Curr Biol. 2010. PMID 21035343.
• "ELMO1 is upregulated in AML CD34+ stem/progenitor cells, mediates chemotaxis and predicts poor prognosis in normal karyotype AML. ". PLoS One. 2014. PMID 25360637.
• "[Polymorphism g.37190613 G>A of the ELMO1 gene in the Mexican population: potential marker for clinical-surgical pathology]. ". Cir Cir. 2014. PMID 25167351.
• "Association of ELMO1 gene polymorphisms with diabetic nephropathy in Chinese population.". J Endocrinol Invest. 2013. PMID 22842811.