ESYT2

Protein sy'n cael ei godio yn y corff dynol gan y genyn ESYT2 yw ESYT2 a elwir hefyd yn Extended synaptotagmin 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q36.3.

ESYT2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2DMG, 4NPJ, 4NPK, 4P42
Dynodwyr
Cyfenwau	ESYT2, CHR2SYT, E-Syt2, FAM62B, extended synaptotagmin protein 2, extended synaptotagmin 2
Dynodwyr allanol	OMIM: 616691 HomoloGene: 32699 GeneCards: ESYT2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium-dependent phospholipid binding • calcium ion binding • GO:0001948, GO:0016582 protein binding • metal ion binding • phosphatidylinositol binding • phosphatidylethanolamine binding • phosphatidylcholine binding • identical protein binding • lipid binding • cadherin binding Cydrannau o'r gell • intrinsic component of endoplasmic reticulum membrane • organelle membrane contact site • integral component of membrane • extrinsic component of cytoplasmic side of plasma membrane • Cellbilen • integral component of plasma membrane • bilen • Reticwlwm endoplasmig • endoplasmic reticulum membrane • endoplasmic reticulum-plasma membrane contact site Prosesau biolegol • lipid transport • endocytosis • glycosphingolipid metabolic process • GO:0015915 transport • endoplasmic reticulum-plasma membrane tethering Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	57488	n/a
Ensembl	ENSG00000117868	n/a
UniProt	A0FGR8	n/a
RefSeq (mRNA)	NM_020728	n/a
RefSeq (protein)	NP_065779 NP_001354702	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ESYT2.

• E-Syt2
• FAM62B
• CHR2SYT

Llyfryddiaeth

• "E-Syts, a family of membranous Ca2+-sensor proteins with multiple C2 domains. ". Proc Natl Acad Sci U S A. 2007. PMID 17360437.
• "PI(4,5)P(2)-dependent and Ca(2+)-regulated ER-PM interactions mediated by the extended synaptotagmins. ". Cell. 2013. PMID 23791178.
• "Structure of a lipid-bound extended synaptotagmin indicates a role in lipid transfer. ". Nature. 2014. PMID 24847877.
• "Structure and Ca²⁺-binding properties of the tandem Câ‚‚ domains of E-Syt2. ". Structure. 2014. PMID 24373768.
• "Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity.". J Biol Chem. 2015. PMID 25922075.