ETS2

Protein sy'n cael ei godio yn y corff dynol gan y genyn ETS2 yw ETS2 a elwir hefyd yn Protein C-ets-2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 21, band 21q22.2.

ETS2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4BQA, 4MHV
Dynodwyr
Cyfenwau	ETS2, ETS2IT1, ETS proto-oncogene 2, transcription factor
Dynodwyr allanol	OMIM: 164740 HomoloGene: 3838 GeneCards: ETS2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding • glucocorticoid receptor binding • protein domain specific binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • Cellbilen • nucleoplasm • cnewyllyn cell • cytosol Prosesau biolegol • skeletal system development • cell differentiation • GO:0009373 regulation of transcription, DNA-templated • GO:1901227 negative regulation of transcription by RNA polymerase II • transcription, DNA-templated • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • ectodermal cell fate commitment • mesoderm development • primitive streak formation • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2114	n/a
Ensembl	ENSG00000157557	n/a
UniProt	P15036	n/a
RefSeq (mRNA)	NM_001256295 NM_005239	n/a
RefSeq (protein)	NP_001243224 NP_005230	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ETS2.

• ETS2IT1

Llyfryddiaeth

• "A genetic variation in microRNA target site of ETS2 is associated with clinical outcomes of paclitaxel-cisplatin chemotherapy in non-small cell lung cancer. ". Oncotarget. 2016. PMID 26893365.
• "Structural insights into the autoregulation and cooperativity of the human transcription factor Ets-2. ". J Biol Chem. 2015. PMID 25670864.
• "Role for Ets-2(Thr-72) transcription factor in stage-specific thymocyte development and survival. ". J Biol Chem. 2012. PMID 22128184.
• "Differential allelic distribution of V-ets erythroblastosis virus E26 oncogene homolog2 (ETS2) functional polymorphisms in different group of patients. ". Gene Expr. 2010. PMID 21526717.
• "Effect of different biomaterials on the expression pattern of the transcription factor Ets2 in bone-like constructs.". J Craniomaxillofac Surg. 2009. PMID 19318269.