ADCY5

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADCY5 yw ADCY5 a elwir hefyd yn Adenylate cyclase 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 3, band 3q21.1.

ADCY5
Dynodwyr
Cyfenwau	ADCY5, AC5, FDFM, adenylate cyclase 5, DSKOD
Dynodwyr allanol	OMIM: 600293 HomoloGene: 11213 GeneCards: ADCY5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • adenylate cyclase binding • metal ion binding • lyase activity • protein heterodimerization activity • adenylate cyclase activity • phosphorus-oxygen lyase activity • ATP binding • scaffold protein binding • guanylate cyclase activity Cydrannau o'r gell • integral component of membrane • cell projection • bilen • Cellbilen • cilium • intermediate filament cytoskeleton • guanylate cyclase complex, soluble • integral component of plasma membrane Prosesau biolegol • cAMP biosynthetic process • G protein-coupled adenosine receptor signaling pathway • adenylate cyclase-activating dopamine receptor signaling pathway • regulation of insulin secretion involved in cellular response to glucose stimulus • GO:0007243 intracellular signal transduction • cellular response to forskolin • adenylate cyclase-activating G protein-coupled receptor signaling pathway • locomotory behavior • neuromuscular process controlling balance • positive regulation of cytosolic calcium ion concentration • cellular response to glucagon stimulus • cyclic nucleotide biosynthetic process • adenylate cyclase-inhibiting dopamine receptor signaling pathway • renal water homeostasis • cGMP biosynthetic process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway • activation of adenylate cyclase activity • activation of protein kinase A activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	111	n/a
Ensembl	ENSG00000173175	n/a
UniProt	O95622	n/a
RefSeq (mRNA)	NM_001199642 NM_183357 NM_001378259	n/a
RefSeq (protein)	NP_001186571 NP_899200 NP_001365188	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADCY5.

• AC5
• FDFM

Llyfryddiaeth

• "A Type 2 Diabetes-Associated Functional Regulatory Variant in a Pancreatic Islet Enhancer at the ADCY5Locus. ". Diabetes. 2017. PMID 28684635.
• "Alternating Hemiplegia of Childhood as a New Presentation of Adenylate Cyclase 5-Mutation-Associated Disease: A Report of Two Cases. ". J Pediatr. 2017. PMID 27931826.
• "Phenotypic insights into ADCY5-associated disease. ". Mov Disord. 2016. PMID 27061943.
• "ADCY5 mutation carriers display pleiotropic paroxysmal day and nighttime dyskinesias. ". Mov Disord. 2016. PMID 26686870.
• "ADCY5 mutations are another cause of benign hereditary chorea.". Neurology. 2015. PMID 26085604.