ADCY6

Protein sy'n cael ei godio yn y corff dynol gan y genyn ADCY6 yw ADCY6 a elwir hefyd yn Adenylate cyclase 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q13.12.

ADCY6
Dynodwyr
Cyfenwau	ADCY6, AC6, LCCS8, adenylate cyclase 6
Dynodwyr allanol	OMIM: 600294 HomoloGene: 22400 GeneCards: ADCY6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • metal ion binding • nucleotide binding • lyase activity • protein kinase binding • adenylate cyclase activity • phosphorus-oxygen lyase activity • ATP binding • GO:0001948, GO:0016582 protein binding • guanylate cyclase activity • protein kinase C binding Cydrannau o'r gell • integral component of membrane • cell projection • intrinsic component of plasma membrane • bilen • cilium • Cellbilen • guanylate cyclase complex, soluble • intracellular anatomical structure • integral component of plasma membrane • stereocilium Prosesau biolegol • negative regulation of neuron projection development • GO:0007243 intracellular signal transduction • cAMP biosynthetic process • cellular response to forskolin • negative regulation of urine volume • cellular response to glucagon stimulus • cyclic nucleotide biosynthetic process • cellular response to vasopressin • cellular response to catecholamine stimulus • cellular response to prostaglandin E stimulus • dopamine receptor signaling pathway • adenylate cyclase-activating G protein-coupled receptor signaling pathway • renal water homeostasis • cGMP biosynthetic process • adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway • blood vessel diameter maintenance • G protein-coupled receptor signaling pathway • activation of adenylate cyclase activity • activation of protein kinase A activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	112	n/a
Ensembl	ENSG00000174233	n/a
UniProt	O43306	n/a
RefSeq (mRNA)	NM_015270 NM_020983 NM_001390830 NM_001390831	n/a
RefSeq (protein)	NP_056085	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ADCY6.

• AC6
• LCCS8

Llyfryddiaeth

• "Association of adenylyl cyclase 6 rs3730070 polymorphism and hemolytic level in patients with sickle cell anemia. ". Blood Cells Mol Dis. 2016. PMID 27067484.
• "Increased blood pressure and hyperdynamic cardiovascular responses in carriers of a common hyperfunctional variant of adenylyl cyclase 6. ". J Pharmacol Exp Ther. 2010. PMID 20732959.
• "Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6. ". J Physiol. 2009. PMID 19546162.
• "The C1 and C2 domains target human type 6 adenylyl cyclase to lipid rafts and caveolae. ". Cell Signal. 2009. PMID 19007881.
• "Adenylylcyclase gene transfer increases function of the failing heart.". Hum Gene Ther. 2006. PMID 17007567.