AIMP1

Protein sy'n cael ei godio yn y corff dynol gan y genyn AIMP1 yw AIMP1 a elwir hefyd yn Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 ac Aminoacyl tRNA synthetase complex interacting multifunctional protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q24.

AIMP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1E7Z, 1EUJ, 1FL0, 4R3Z
Dynodwyr
Cyfenwau	AIMP1, EMAP2, EMAPII, HLD3, SCYE1, p43, aminoacyl tRNA synthetase complex interacting multifunctional protein 1
Dynodwyr allanol	OMIM: 603605 HomoloGene: 31260 GeneCards: AIMP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein homodimerization activity • GO:0001948, GO:0016582 protein binding • RNA binding • GTPase binding • tRNA binding • cytokine activity Cydrannau o'r gell • Golgi apparatus • bilen • aminoacyl-tRNA synthetase multienzyme complex • transport vesicle • extracellular region • cell surface • Reticwlwm endoplasmig • GO:0016023 cytoplasmic vesicle • cnewyllyn cell • methionyl glutamyl tRNA synthetase complex • extracellular space • cytoplasm • cytosol Prosesau biolegol • blood vessel morphogenesis • protein biosynthesis • cell-cell signaling • negative regulation of endothelial cell proliferation • chemotaxis • cell adhesion • defense response to virus • response to wounding • angiogenesis • glucose metabolic process • leukocyte migration • GO:0072468 signal transduction • GO:0097285 apoptotic process • tRNA aminoacylation for protein translation • inflammatory response • carbohydrate metabolic process • regulation of signaling receptor activity • positive regulation of glucagon secretion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9255	n/a
Ensembl	ENSG00000164022	n/a
UniProt	Q12904	n/a
RefSeq (mRNA)	NM_004757 NM_001142415 NM_001142416	n/a
RefSeq (protein)	NP_001135887 NP_001135888 NP_004748	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AIMP1.

• p43
• HLD3
• EMAP2
• SCYE1
• EMAPII

Llyfryddiaeth

• "Missense variants in AIMP1 gene are implicated in autosomal recessive intellectual disability without neurodegeneration. ". Eur J Hum Genet. 2016. PMID 26173967.
• "Endothelial monocyte activating polypeptide II in children and adolescents with type 1 diabetes mellitus: Relation to micro-vascular complications. ". Cytokine. 2015. PMID 26142824.
• "[SERUM LEVEL OF ENDOTHELIAL MONOCYTE ACTIVATING POLYPEPTIDE-II IN CHILDHOOD-ONSET TYPE 1 DIABETIC PATIENTS AND OBESE ADOLESCENTS]. ". Lik Sprava. 2015. PMID 27089716.
• "AIMP1 downregulation restores chondrogenic characteristics of dedifferentiated/degenerated chondrocytes by enhancing TGF-β signal. ". Cell Death Dis. 2016. PMID 26890138.
• "Stepping Out of the Cytosol: AIMp1/p43 Potentiates the Link Between Innate and Adaptive Immunity.". Int Rev Immunol. 2015. PMID 26325028.