AMBP

Protein sy'n cael ei godio yn y corff dynol gan y genyn AMBP yw AMBP a elwir hefyd yn Alpha-1-microglobulin/bikunin precursor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q32.

AMBP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BIK, 3QKG, 4ES7, 4U30
Dynodwyr
Cyfenwau	AMBP, A1M, EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI, alpha-1-microglobulin/bikunin precursor
Dynodwyr allanol	OMIM: 176870 HomoloGene: 1234 GeneCards: AMBP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • peptidase inhibitor activity • calcium channel inhibitor activity • protein homodimerization activity • calcium oxalate binding • GO:0001948, GO:0016582 protein binding • heme binding • serine-type endopeptidase inhibitor activity • small molecule binding • IgA binding Cydrannau o'r gell • blood microparticle • intracellular membrane-bounded organelle • Cellbilen • extracellular region • cell surface • extracellular exosome • extracellular space • GO:0005578 extracellular matrix • collagen-containing extracellular matrix Prosesau biolegol • negative regulation of peptidase activity • female pregnancy • receptor-mediated endocytosis • negative regulation of JNK cascade • heme catabolic process • negative regulation of immune response • cell adhesion • GO:0044257 protein catabolic process • GO:0022415 viral process • negative regulation of endopeptidase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	259	n/a
Ensembl	ENSG00000106927	n/a
UniProt	P02760	n/a
RefSeq (mRNA)	NM_001633	n/a
RefSeq (protein)	NP_001624	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AMBP.

• A1M
• HCP
• ITI
• UTI
• EDC1
• HI30
• ITIL
• IATIL
• ITILC

Llyfryddiaeth

• "Structural and biochemical characterization of two heme binding sites on α1-microglobulin using site directed mutagenesis and molecular simulation. ". Biochim Biophys Acta. 2016. PMID 26497278.
• "High-level secretion of human bikunin from recombinant Pichia pastoris. ". Lett Appl Microbiol. 2015. PMID 26202000.
• "Urinary trypsin inhibitor levels are reduced in cerebrospinal fluid of multiple sclerosis and neuromyelitis optica patients during relapse. ". Neurochem Int. 2015. PMID 25555815.
• "Association of urine α1-microglobulin with kidney function decline and mortality in HIV-infected women. ". Clin J Am Soc Nephrol. 2015. PMID 25370597.
• "Reduced gene expression of bikunin as a prognostic marker for renal cell carcinoma.". Exp Oncol. 2014. PMID 24980765.