AMFR

Protein sy'n cael ei godio yn y corff dynol gan y genyn AMFR yw AMFR a elwir hefyd yn Autocrine motility factor receptor (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q13.

AMFR
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2EJS, 2LVN, 2LVO, 2LVP, 2LVQ, 2LXH, 2LXP, 3FSH, 3H8K, 3TIW, 4G3O, 4LAD
Dynodwyr
Cyfenwau	AMFR, GP78, RNF45, autocrine motility factor receptor
Dynodwyr allanol	OMIM: 603243 HomoloGene: 888 GeneCards: AMFR
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein-macromolecule adaptor activity • chaperone binding • GO:1904264, GO:1904822, GO:0090622, GO:0090302 ubiquitin protein ligase activity • metal ion binding • GO:0050372 ubiquitin-protein transferase activity • ubiquitin-ubiquitin ligase activity • GO:0001948, GO:0016582 protein binding • ubiquitin-specific protease binding • transferase activity • identical protein binding • BAT3 complex binding • signaling receptor activity Cydrannau o'r gell • cytoplasm • integral component of membrane • bilen • growth cone • integral component of endoplasmic reticulum membrane • soma • dendrite • Derlin-1 retrotranslocation complex • perinuclear region of cytoplasm • cnewyllyn cell • Reticwlwm endoplasmig • endoplasmic reticulum membrane • Golgi apparatus • endoplasmic reticulum quality control compartment • GO:0009327 protein-containing complex • ubiquitin ligase complex • cytosol Prosesau biolegol • ERAD pathway • ubiquitin-dependent protein catabolic process • GO:0010260 heneiddio • protein polyubiquitination • endoplasmic reticulum unfolded protein response • protein K48-linked ubiquitination • protein complex oligomerization • protein ubiquitination • ubiquitin-dependent ERAD pathway • learning or memory • positive regulation of protein binding • GO:0072468 signal transduction • protein autoubiquitination • protein folding • endoplasmic reticulum mannose trimming Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	267	n/a
Ensembl	ENSG00000159461	n/a
UniProt	Q9UKV5	n/a
RefSeq (mRNA)	NM_001144 NM_138958 NM_001323511 NM_001323512	n/a
RefSeq (protein)	NP_001135 NP_001310440 NP_001310441	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AMFR.

• GP78
• RNF45

Llyfryddiaeth

• "Autocrine motility factor receptor promotes the proliferation of human acute monocytic leukemia THP-1 cells. ". Int J Mol Med. 2015. PMID 26136223.
• "Affinity proteomics discovers decreased levels of AMFR in plasma from Osteoporosis patients. ". Proteomics Clin Appl. 2016. PMID 25689831.
• "Aberrant expression of the autocrine motility factor receptor correlates with poor prognosis and promotes metastasis in gastric carcinoma. ". Asian Pac J Cancer Prev. 2014. PMID 24568530.
• "gp78 is specifically expressed in human prostate cancer rather than normal prostate tissue. ". J Mol Histol. 2013. PMID 23666464.
• "gp78: a multifaceted ubiquitin ligase that integrates a unique protein degradation pathway from the endoplasmic reticulum.". Curr Protein Pept Sci. 2012. PMID 22812524.