ANK1

Protein sy'n cael ei godio yn y corff dynol gan y genyn ANK1 yw ANK1 a elwir hefyd yn Ankyrin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 8, band 8p11.21.

ANK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1N11, 2YQF, 2YVI, 3F59, 3KBT, 3KBU, 3UD1, 3UD2
Dynodwyr
Cyfenwau	ANK1, ANK, SPH1, SPH2, ankyrin 1
Dynodwyr allanol	OMIM: 612641 HomoloGene: 55427 GeneCards: ANK1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • spectrin binding • ATPase binding • structural molecule activity • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • enzyme binding • cytoskeletal anchor activity Cydrannau o'r gell • M band • cytosol • postsynaptic membrane • bilen • Cellbilen • sarcoplasmic reticulum • basolateral plasma membrane • Z disc • axolemma • spectrin-associated cytoskeleton • neuron projection • sarcolemma • A band • Cytosgerbwd • cnewyllyn cell • cytoplasm Prosesau biolegol • positive regulation of organelle organization • endoplasmic reticulum to Golgi vesicle-mediated transport • maintenance of epithelial cell apical/basal polarity • cytoskeleton organization • GO:0072468 signal transduction • exocytosis • protein localization to plasma membrane Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	286	n/a
Ensembl	ENSG00000029534	n/a
UniProt	P16157	n/a
RefSeq (mRNA)	NM_000037 NM_001142445 NM_001142446 NM_020475 NM_020476 NM_020477 NM_020478 NM_020479 NM_020480 NM_020481	n/a
RefSeq (protein)	NP_000028 NP_001135917 NP_001135918 NP_065208 NP_065209 NP_065210 NP_065211 NP_065213	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ANK1.

• ANK
• SPH1
• SPH2

Llyfryddiaeth

• "ANK1 Methylation regulates expression of MicroRNA-486-5p and discriminates lung tumors by histology and smoking status. ". Cancer Lett. 2017. PMID 28965852.
• "ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity. ". PLoS One. 2017. PMID 28700589.
• "The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. ". Cell Death Dis. 2016. PMID 27054339.
• "Identification of a novel p.Q1772X ANK1 mutation in a Korean family with hereditary spherocytosis. ". PLoS One. 2015. PMID 26107955.
• "Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease.". Nat Neurosci. 2014. PMID 25129077.