ANXA5

Protein sy'n cael ei godio yn y corff dynol gan y genyn ANXA5 yw ANXA5 a elwir hefyd yn Annexin A5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q27.

ANXA5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2XO3, 1ANW, 1ANX, 1AVH, 1AVR, 1HAK, 1HVD, 1HVE, 1HVF, 1HVG, 1SAV, 2XO2
Dynodwyr
Cyfenwau	ANXA5, ANX5, ENX2, HEL-S-7, PP4, RPRGL3, annexin A5, CPB-I, VAC-alph
Dynodwyr allanol	OMIM: 131230 HomoloGene: 20312 GeneCards: ANXA5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • phospholipase inhibitor activity • calcium ion binding • GO:0001948, GO:0016582 protein binding • calcium-dependent phospholipid binding • phospholipid binding • P-type calcium transporter activity • heparin binding • peptide hormone binding • receptor tyrosine kinase binding • GO:0032947 molecular adaptor activity Cydrannau o'r gell • bilen • focal adhesion • intracellular anatomical structure • endothelial microparticle • extracellular exosome • external side of plasma membrane • extracellular region • cytoplasm • cytosol • collagen-containing extracellular matrix Prosesau biolegol • hemostasis • negative regulation of coagulation • blood coagulation • negative regulation of apoptotic process • response to organic substance • GO:0072468 signal transduction • GO:0048553 negative regulation of catalytic activity • platelet degranulation • negative regulation of blood coagulation • positive regulation of apoptotic process • protein homooligomerization • negative regulation of sequestering of calcium ion • response to calcium ion • calcium ion transmembrane transport • cellular response to lead ion • response to thyroid hormone • cellular response to gonadotropin-releasing hormone • regulation of flagellated sperm motility • negative regulation of prolactin secretion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	308	n/a
Ensembl	ENSG00000164111	n/a
UniProt	P08758	n/a
RefSeq (mRNA)	NM_001154	n/a
RefSeq (protein)	NP_001145	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ANXA5.

• PP4
• ANX5
• ENX2
• RPRGL3
• HEL-S-7

Llyfryddiaeth

• "The association between annexin A5 (ANXA5) gene polymorphism and left ventricular hypertrophy (LVH) in Chinese endogenous hypertension patients. ". Medicine (Baltimore). 2017. PMID 29095261.
• "Circulating annexin A5 levels are associated with carotid intima-media thickness but not coronary plaque composition. ". Diab Vasc Dis Res. 2017. PMID 28592134.
• "Functional characterization of annexin A5 gene promoter allelic variants. ". Thromb Res. 2016. PMID 27318245.
• "Membrane repair of human skeletal muscle cells requires Annexin-A5. ". Biochim Biophys Acta. 2016. PMID 27286750.
• "Investigation of the Annexin A5 M2 haplotype in 500 white European couples who have experienced recurrent spontaneous abortion.". Reprod Biomed Online. 2015. PMID 26371709.