AP1G1

Protein sy'n cael ei godio yn y corff dynol gan y genyn AP1G1 yw AP1G1 a elwir hefyd yn Adaptor related protein complex 1 gamma 1 subunit (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16q22.2.

AP1G1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1IU1
Dynodwyr
Cyfenwau	AP1G1, ADTG, CLAPG1, adaptor related protein complex 1 gamma 1 subunit, adaptor related protein complex 1 subunit gamma 1, USRISD
Dynodwyr allanol	OMIM: 603533 HomoloGene: 47995 GeneCards: AP1G1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transporter activity • GTP-dependent protein binding • GO:0001948, GO:0016582 protein binding • kinesin binding Cydrannau o'r gell • recycling endosome • clathrin-coated endocytic vesicle membrane • Golgi apparatus • trans-Golgi network membrane • bilen • intracellular membrane-bounded organelle • Golgi membrane • lysosomal membrane • AP-type membrane coat adaptor complex • clathrin-coated vesicle membrane • membrane coat • cytoplasmic vesicle membrane • GO:0016023 cytoplasmic vesicle • clathrin-coated vesicle • clathrin adaptor complex • cytoplasm • cytosol • AP-1 adaptor complex Prosesau biolegol • antigen processing and presentation of exogenous peptide antigen via MHC class II • GO:0019049, GO:0030683 mitigation of host defenses by virus • Golgi to lysosome transport • positive regulation of natural killer cell degranulation • melanosome organization • endosome to melanosome transport • protein transport • intracellular protein transport • positive regulation of natural killer cell mediated cytotoxicity • vesicle-mediated transport • GO:0015915 transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	164	n/a
Ensembl	ENSG00000166747	n/a
UniProt	O43747	n/a
RefSeq (mRNA)	NM_001128 NM_001030007	n/a
RefSeq (protein)	NP_001025178 NP_001119	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AP1G1.

• ADTG
• CLAPG1

Llyfryddiaeth

• "Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes. ". EMBO J. 2003. PMID 12773381.
• "Gamma-adaptin interacts directly with Rabaptin-5 through its ear domain. ". J Biochem. 2002. PMID 11872161.
• "Rab4b controls an early endosome sorting event by interacting with the γ-subunit of the clathrin adaptor complex 1. ". J Cell Sci. 2013. PMID 24006255.
• "Gamma-adaptin, a novel ubiquitin-interacting adaptor, and Nedd4 ubiquitin ligase control hepatitis B virus maturation. ". J Biol Chem. 2006. PMID 16867982.
• "AP1G1 is involved in cetuximab-mediated downregulation of ASCT2-EGFR complex and sensitization of human head and neck squamous cell carcinoma cells to ROS-induced apoptosis.". Cancer Lett. 2017. PMID 28823958.