APBB2

Protein sy'n cael ei godio yn y corff dynol gan y genyn APBB2 yw APBB2 a elwir hefyd yn Amyloid beta precursor protein binding family B member 2 ac Amyloid beta A4 precursor protein-binding family B member 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4p14-p13.

APBB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1WGU, 2ROZ, 2YSZ, 2YT0, 2YT1
Dynodwyr
Cyfenwau	APBB2, FE65L, FE65L1, amyloid beta precursor protein binding family B member 2
Dynodwyr allanol	OMIM: 602710 HomoloGene: 32079 GeneCards: APBB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • transcription factor binding • amyloid-beta binding Cydrannau o'r gell • growth cone • bilen • cytoplasm • lamellipodium • synapse • cnewyllyn cell Prosesau biolegol • positive regulation of apoptotic process • GO:0007243 intracellular signal transduction • negative regulation of cell growth • negative regulation of apoptotic process • extracellular matrix organization • axon guidance • neuron migration • GO:0009373 regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	323	n/a
Ensembl	ENSG00000163697	n/a
UniProt	Q92870	n/a
RefSeq (mRNA)	NM_001166050 NM_001166051 NM_001166052 NM_001166053 NM_001166054 NM_004307 NM_173075 NM_001330656 NM_001330658	n/a
RefSeq (protein)	NP_001159522 NP_001159523 NP_001159524 NP_001159525 NP_001159526 NP_001317585 NP_001317587 NP_004298 NP_775098	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APBB2.

• FE65L
• FE65L1

Llyfryddiaeth

• "Differential processing of amyloid-beta precursor protein directs human embryonic stem cell proliferation and differentiation into neuronal precursor cells. ". J Biol Chem. 2009. PMID 19542221.
• "Analysis of APBB2 gene polymorphisms in sporadic Alzheimer's disease. ". Neurosci Lett. 2008. PMID 18852029.
• "GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension. ". Neurotox Res. 2015. PMID 26194614.
• "APBB2 genetic polymorphisms are associated with severe cognitive impairment in centenarians. ". Exp Gerontol. 2013. PMID 23384821.
• "Genetic association of the APP binding protein 2 gene (APBB2) with late onset Alzheimer disease.". Hum Mutat. 2005. PMID 15714520.