APCS

Protein sy'n cael ei godio yn y corff dynol gan y genyn APCS yw APCS a elwir hefyd yn Amyloid P component, serum (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.2.

APCS
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4AYU, 1GYK, 1LGN, 1SAC, 2A3W, 2A3X, 2A3Y, 2W08, 3D5O, 3KQR, 4AVS, 4AVT, 4AVV
Dynodwyr
Cyfenwau	APCS, HEL-S-92n, PTX2, SAP, amyloid P component, serum
Dynodwyr allanol	OMIM: 104770 HomoloGene: 123932 GeneCards: APCS
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • calcium ion binding • unfolded protein binding • metal ion binding • virion binding • complement component C1q complex binding • carbohydrate binding • identical protein binding • low-density lipoprotein particle binding Cydrannau o'r gell • blood microparticle • GO:0005578 extracellular matrix • extracellular exosome • cnewyllyn cell • extracellular space • extracellular region • collagen-containing extracellular matrix Prosesau biolegol • negative regulation of monocyte differentiation • negative regulation of acute inflammatory response • negative regulation of viral entry into host cell • chaperone-mediated protein complex assembly • negative regulation of viral process • negative regulation of glycoprotein metabolic process • protein folding • acute-phase response • negative regulation of exo-alpha-sialidase activity • negative regulation of wound healing • innate immune response • complement activation, classical pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	325	n/a
Ensembl	ENSG00000132703	n/a
UniProt	P02743	n/a
RefSeq (mRNA)	NM_001639	n/a
RefSeq (protein)	NP_001630	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APCS.

• SAP
• PTX2
• HEL-S-92n

Llyfryddiaeth

• "Serum Amyloid P Component (SAP) Interactome in Human Plasma Containing Physiological Calcium Levels. ". Biochemistry. 2017. PMID 28098450.
• "Interaction of serum amyloid P component with hexanoyl bis(D-proline) (CPHPC). ". Acta Crystallogr D Biol Crystallogr. 2014. PMID 25084341.
• "Distinct Fcγ receptors mediate the effect of serum amyloid p on neutrophil adhesion and fibrocyte differentiation. ". J Immunol. 2014. PMID 25024390.
• "First identification of resident and circulating fibrocytes in Dupuytren's disease shown to be inhibited by serum amyloid P and Xiapex. ". PLoS One. 2014. PMID 24933153.
• "Coordinated proteomic signature changes in immune response and complement proteins in acute myocardial infarction: the implication of serum amyloid P-component.". Int J Cardiol. 2013. PMID 23992930.