APOA2

Protein sy'n cael ei godio yn y corff dynol gan y genyn APOA2 yw APOA2 a elwir hefyd yn Apolipoprotein A2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q23.3.

APOA2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1L6L, 2OU1
Dynodwyr
Cyfenwau	APOA2, Apo-AII, ApoA-II, apoAII, Apolipoprotein A2
Dynodwyr allanol	OMIM: 107670 HomoloGene: 1242 GeneCards: APOA2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • lipase inhibitor activity • protein homodimerization activity • phosphatidylcholine binding • lipid transporter activity • apolipoprotein receptor binding • high-density lipoprotein particle receptor binding • cholesterol binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • phosphatidylcholine-sterol O-acyltransferase activator activity • phospholipid binding • GO:0017127 cholesterol transfer activity • lipid binding • high-density lipoprotein particle binding • heat shock protein binding • signaling receptor binding Cydrannau o'r gell • cytosol • blood microparticle • endoplasmic reticulum lumen • chylomicron • very-low-density lipoprotein particle • spherical high-density lipoprotein particle • extracellular region • early endosome • high-density lipoprotein particle • extracellular exosome • extracellular space Prosesau biolegol • negative regulation of cholesterol import • negative regulation of very-low-density lipoprotein particle remodeling • diacylglycerol catabolic process • lipid transport • regulation of protein stability • positive regulation of cholesterol esterification • phospholipid efflux • cholesterol transport • positive regulation of lipid catabolic process • response to glucocorticoid • GO:0002719 negative regulation of cytokine production involved in immune response • response to glucose • high-density lipoprotein particle assembly • retinoid metabolic process • response to estrogen • high-density lipoprotein particle remodeling • negative regulation of lipase activity • regulation of intestinal cholesterol absorption • low-density lipoprotein particle remodeling • acute inflammatory response • animal organ regeneration • phospholipid catabolic process • peptidyl-methionine modification • cholesterol efflux • negative regulation of cholesterol transport • cholesterol homeostasis • phosphatidylcholine biosynthetic process • negative regulation of cholesterol transporter activity • GO:0022415 viral process • negative regulation of lipid catabolic process • triglyceride-rich lipoprotein particle remodeling • triglyceride metabolic process • reverse cholesterol transport • high-density lipoprotein particle clearance • GO:0048554 positive regulation of catalytic activity • cholesterol metabolic process • regulation of lipid metabolic process • chylomicron remodeling • chylomicron assembly • lipoprotein metabolic process • post-translational protein modification • GO:0015915 transport • positive regulation of phagocytosis • protein stabilization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	336	n/a
Ensembl	ENSG00000158874	n/a
UniProt	P02652	n/a
RefSeq (mRNA)	NM_001643	n/a
RefSeq (protein)	NP_001634	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn APOA2.

• apoAII
• Apo-AII
• ApoA-II

Llyfryddiaeth

• "Apolipoprotein A2 -265 T>C polymorphism interacts with dietary fatty acids intake to modulate inflammation in type 2 diabetes mellitus patients. ". Nutrition. 2017. PMID 28359369.
• "Identification of Sequence Variation in the Apolipoprotein A2 Gene and Their Relationship with Serum High-Density Lipoprotein Cholesterol Levels. ". Iran Biomed J. 2016. PMID 26590203.
• "Plasma biomarker for detection of early stage pancreatic cancer and risk factors for pancreatic malignancy using antibodies for apolipoprotein-AII isoforms. ". Sci Rep. 2015. PMID 26549697.
• "Association between ApoA-II -265T/C polymorphism and oxidative stress in patients with type 2 diabetes mellitus. ". J Diabetes Complications. 2015. PMID 26104730.
• "Apolipoprotein AII levels are associated with the UP/UCr levels in idiopathic steroid-sensitive nephrotic syndrome.". Clin Exp Nephrol. 2015. PMID 24633472.