ARFGAP1

ARFGAP1
Strwythurau
PDB	Human UniProt search: PDBe RCSB
Rhestr o ddynodwyr PDB
	3O47, 3DWD
Dynodwyr
Cyfenwau	ARFGAP1, ARF1GAP, HRIHFB2281, ADP ribosylation factor GTPase activating protein 1
Dynodwyr allanol	OMIM: 608377 HomoloGene: 5517 GeneCards: ARFGAP1
Patrwm RNA pattern
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• metal ion binding; • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity; • GO:0001948, GO:0016582 protein binding;
Cydrannau o'r gell	• cytoplasm; • synapse; • Golgi apparatus; • cytosol; • GO:0097483, GO:0097481 postsynaptic density; • Golgi membrane;
Prosesau biolegol	• endoplasmic reticulum to Golgi vesicle-mediated transport; • regulation of endocytosis; • IRE1-mediated unfolded protein response; • retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; • protein transport; • vesicle-mediated transport; • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity; • regulation of ARF protein signal transduction;
	Sources:Amigo / QuickGO
Orthologau
	55738
	n/a
	ENSG00000101199
	n/a
	Q8N6T3
	n/a
	NM_001281482; NM_001281483; NM_001281484; NM_018209; NM_175609
	n/a
	NP_001268411; NP_001268412; NP_001268413; NP_060679; NP_783202
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARFGAP1 yw ARFGAP1 a elwir hefyd yn ADP-ribosylation factor GTPase-activating protein 1 ac ADP ribosylation factor GTPase activating protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20q13.33.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARFGAP1.

ARF1GAP
HRIHFB2281

Llyfryddiaeth

"GAP control: regulating the regulators of small GTPases. ". Trends Cell Biol. 2004. PMID 15246431.
"Expression, purification, and properties of ADP-ribosylation factor (ARF) GTPase activating protein-1. ". Methods Enzymol. 2001. PMID 11210549.
"ARFGAP1 is dynamically associated with lipid droplets in hepatocytes. ". PLoS One. 2014. PMID 25397679.
"ArfGAP1 activity and COPI vesicle biogenesis. ". Traffic. 2009. PMID 19055691.
"Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer.". J Biol Chem. 2008. PMID 18541532.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] ARFGAP1 - Cronfa NCBI

[2]

[1]