ARHGAP26

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARHGAP26 yw ARHGAP26 a elwir hefyd yn Rho GTPase-activating protein 26 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 5, band 5q31.3.

ARHGAP26
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UGV
Dynodwyr
Cyfenwau	ARHGAP26, GRAF, GRAF1, OPHN1L, OPHN1L1, Rho GTPase activating protein 26
Dynodwyr allanol	OMIM: 605370 HomoloGene: 36349 GeneCards: ARHGAP26
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • phospholipid binding • GO:0005097, GO:0005099, GO:0005100 GTPase activator activity Cydrannau o'r gell • cytoplasm • cytosol • cell junction • Cytosgerbwd • focal adhesion • cydran cellog Prosesau biolegol • regulation of small GTPase mediated signal transduction • actin cytoskeleton organization • nervous system development • GO:0072468 signal transduction • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23092	n/a
Ensembl	ENSG00000145819	n/a
UniProt	Q9UNA1	n/a
RefSeq (mRNA)	NM_001135608 NM_015071 NM_001349547	n/a
RefSeq (protein)	NP_001129080 NP_055886 NP_001336476	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARHGAP26.

• GRAF
• GRAF1
• OPHN1L
• OPHN1L1

Llyfryddiaeth

• "GTPase regulator associated with the focal adhesion kinase (GRAF) transcript was down-regulated in patients with myeloid malignancies. ". J Exp Clin Cancer Res. 2010. PMID 20704716.
• "Decreased expression of GRAF1/OPHN-1-L in the X-linked alpha thalassemia mental retardation syndrome. ". BMC Med Genomics. 2010. PMID 20602808.
• "High expression of GTPase regulator associated with the focal adhesion kinase (GRAF) is a favorable prognostic factor in acute myeloid leukemia. ". Blood Cells Mol Dis. 2014. PMID 25088035.
• "The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. ". Mol Biol Cell. 2011. PMID 21965292.
• "Abnormal methylation of GRAF promoter Chinese patients with acute myeloid leukemia.". Leuk Res. 2011. PMID 21074269.