ARHGEF9

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARHGEF9 yw ARHGEF9 a elwir hefyd yn Rho guanine nucleotide exchange factor 9 a Cdc42 guanine nucleotide exchange factor 9 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom X dynol, band Xq11.1.

ARHGEF9
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2YSQ
Dynodwyr
Cyfenwau	ARHGEF9, COLLYBISTIN, EIEE8, HPEM-2, PEM-2, PEM2, Cdc42 guanine nucleotide exchange factor 9, DEE8
Dynodwyr allanol	OMIM: 300429 HomoloGene: 9053 GeneCards: ARHGEF9
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • guanyl-nucleotide exchange factor activity Cydrannau o'r gell • cytoplasm • cytosol • GO:0097483, GO:0097481 postsynaptic density • GABA-ergic synapse • Cellbilen • bilen • cell junction • synapse • postsynaptic membrane Prosesau biolegol • positive regulation of apoptotic process • regulation of Rho protein signal transduction • regulation of small GTPase mediated signal transduction • G protein-coupled receptor signaling pathway • regulation of postsynaptic specialization assembly Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	23229	n/a
Ensembl	ENSG00000131089	n/a
UniProt	O43307	n/a
RefSeq (mRNA)	NM_001173479 NM_001173480 NM_015185 NM_001330495 NM_001353921 NM_001353922 NM_001353923 NM_001353924 NM_001353926 NM_001353927 NM_001353928 NM_001369030 NM_001369031 NM_001369032 NM_001369033 NM_001369034 NM_001369035 NM_001369036 NM_001369037 NM_001369038 NM_001369039 NM_001369040 NM_001369041 NM_001369042 NM_001369043 NM_001369044 NM_001369045	n/a
RefSeq (protein)	NP_001166950 NP_001166951 NP_001317424 NP_056000 NP_001340850 NP_001340851 NP_001340852 NP_001340853 NP_001340855 NP_001340856 NP_001340857 NP_001355959 NP_001355960 NP_001355961 NP_001355962 NP_001355963 NP_001355964 NP_001355965 NP_001355966 NP_001355967 NP_001355968 NP_001355969 NP_001355970 NP_001355971 NP_001355972 NP_001355973 NP_001355974	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARHGEF9.

• PEM2
• EIEE8
• PEM-2
• HPEM-2
• COLLYBISTIN

Llyfryddiaeth

• "Collybistin splice variants differentially interact with gephyrin and Cdc42 to regulate gephyrin clustering at GABAergic synapses. ". J Cell Sci. 2011. PMID 21807943.
• "Loss-of-function mutation of collybistin is responsible for X-linked mental retardation associated with epilepsy. ". J Hum Genet. 2011. PMID 21633362.
• "Xq11.1-11.2 deletion involving ARHGEF9 in a girl with autism spectrum disorder. ". Eur J Med Genet. 2016. PMID 27238888.
• "Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability. ". J Biol Chem. 2015. PMID 25678704.
• "Gs and Gq signalings regulate hPEM-2-induced cell responses in Neuro-2a cells.". Biochem Biophys Res Commun. 2011. PMID 22033413.