ARPC5

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARPC5 yw ARPC5 a elwir hefyd yn Actin related protein 2/3 complex subunit 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1q25.3.

ARPC5
Dynodwyr
Cyfenwau	ARPC5, ARC16, dJ127C7.3, p16-Arc, actin related protein 2/3 complex subunit 5
Dynodwyr allanol	OMIM: 604227 HomoloGene: 4176 GeneCards: ARPC5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • actin filament binding • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • actin binding Cydrannau o'r gell • cytoplasm • cytosol • cell projection • focal adhesion • arp2/3 protein complex • actin cytoskeleton • extracellular exosome • Cytosgerbwd • neuron projection • extracellular region • endosome • growth cone • secretory granule lumen • ficolin-1-rich granule lumen • lamellipodium • cnewyllyn cell • site of double-strand break Prosesau biolegol • Fc-gamma receptor signaling pathway involved in phagocytosis • ephrin receptor signaling pathway • regulation of actin filament polymerization • Arp2/3 complex-mediated actin nucleation • cell migration • actin cytoskeleton organization • actin filament network formation • orbitofrontal cortex development • lamellipodium organization • smooth muscle cell migration • maintenance of cell polarity • neutrophil degranulation • membrane organization • microtubule organizing center localization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	10092	n/a
Ensembl	ENSG00000162704	n/a
UniProt	O15511	n/a
RefSeq (mRNA)	NM_005717 NM_001270439	n/a
RefSeq (protein)	NP_001257368 NP_005708	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARPC5.

• ARC16
• p16-Arc
• dJ127C7.3

Llyfryddiaeth

• "Rear polarization of the microtubule-organizing center in neointimal smooth muscle cells depends on PKCα, ARPC5, and RHAMM. ". Am J Pathol. 2011. PMID 21281821.
• "Identification of the p16-Arc subunit of the Arp 2/3 complex as a substrate of MAPK-activated protein kinase 2 by proteomic analysis. ". J Biol Chem. 2003. PMID 12829704.
• "Actin-related protein 2/3 complex subunit 5 (ARPC5) contributes to cell migration and invasion and is directly regulated by tumor-suppressive microRNA-133a in head and neck squamous cell carcinoma. ". Int J Oncol. 2012. PMID 22378351.
• "Identification and characterisation of a novel human isoform of Arp2/3 complex subunit p16-ARC/ARPC5. ". Cell Motil Cytoskeleton. 2003. PMID 12451597.
• "Tumor suppressive microRNA-133a regulates novel molecular networks in lung squamous cell carcinoma.". J Hum Genet. 2012. PMID 22089643.