ATF1

Protein sy'n cael ei godio yn y corff dynol gan y genyn ATF1 yw ATF1 a elwir hefyd yn Activating transcription factor 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.12.

ATF1
Dynodwyr
Cyfenwau	ATF1, EWS-FUS/ATF-1, TREB36, activating transcription factor 1
Dynodwyr allanol	OMIM: 123803 HomoloGene: 3790 GeneCards: ATF1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • sequence-specific DNA binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding • identical protein binding • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific • GO:0032403 protein-containing complex binding Cydrannau o'r gell • ATF1-ATF4 transcription factor complex • transcription regulator complex • nucleoplasm • cnewyllyn cell Prosesau biolegol • GO:0009373 regulation of transcription, DNA-templated • GO:1904578 response to organic cyclic compound • transcription, DNA-templated • positive regulation of DNA replication • positive regulation of neuron projection development • response to cobalt ion • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • transcription by RNA polymerase II • GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	466	n/a
Ensembl	ENSG00000123268	n/a
UniProt	P18846	n/a
RefSeq (mRNA)	NM_005171	n/a
RefSeq (protein)	NP_005162	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ATF1.

• TREB36
• EWS-ATF1
• FUS/ATF-1

Llyfryddiaeth

• "5'-AMP-activated protein kinase-activating transcription factor 1 cascade modulates human monocyte-derived macrophages to atheroprotective functions in response to heme or metformin. ". Arterioscler Thromb Vasc Biol. 2013. PMID 24051143.
• "Activating transcription factor 1 is a prognostic marker of colorectal cancer. ". Asian Pac J Cancer Prev. 2012. PMID 22631637.
• "Activating transcription factor 1 directs Mhem atheroprotective macrophages through coordinated iron handling and foam cell protection. ". Circ Res. 2012. PMID 22052915.
• "Composition and function of AP-1 transcription complexes during muscle cell differentiation. ". J Biol Chem. 2002. PMID 11877423.
• "Promoter elements and transcription factors involved in differentiation-dependent human chorionic gonadotrophin-alpha messenger ribonucleic acid expression of term villous trophoblasts.". Endocrinology. 2000. PMID 11014230.