AZGP1

Protein sy'n cael ei godio yn y corff dynol gan y genyn AZGP1 yw AZGP1 a elwir hefyd yn Alpha-2-glycoprotein 1, zinc-binding (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7q22.1.

AZGP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1T7V, 1T7W, 1T7X, 1T7Y, 1T7Z, 1T80, 1ZAG, 3ES6
Dynodwyr
Cyfenwau	AZGP1, ZA2G, ZAG, alpha-2-glycoprotein 1, zinc-binding
Dynodwyr allanol	OMIM: 194460 HomoloGene: 915 GeneCards: AZGP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein transmembrane transporter activity • ribonuclease activity • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • Cellbilen • extracellular exosome • cnewyllyn cell • extracellular space • GO:0005578 extracellular matrix • extracellular region • collagen-containing extracellular matrix • external side of plasma membrane Prosesau biolegol • detection of chemical stimulus involved in sensory perception of bitter taste • retina homeostasis • cell adhesion • transmembrane transport • negative regulation of cell population proliferation • protein transmembrane transport • RNA phosphodiester bond hydrolysis • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	563	n/a
Ensembl	ENSG00000160862	n/a
UniProt	P25311	n/a
RefSeq (mRNA)	NM_001185	n/a
RefSeq (protein)	NP_001176	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn AZGP1.

• ZAG
• ZA2G

Llyfryddiaeth

• "Downregulation of AZGP1 by Ikaros and histone deacetylase promotes tumor progression through the PTEN/Akt and CD44s pathways in hepatocellular carcinoma. ". Carcinogenesis. 2017. PMID 27993894.
• "In the search of novel urine biomarkers for the early diagnosis of prostate cancer. Intracellular or secreted proteins as the target group? Where and how to search for possible biomarkers useful in the everyday clinical practice. ". Arch Ital Urol Androl. 2016. PMID 27711093.
• "Loss of AZGP1 as a Superior Predictor of Relapse in Margin-Positive Localized Prostate Cancer. ". Prostate. 2016. PMID 27473574.
• "Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort. ". Prostate. 2016. PMID 27325561.
• "Zinc alpha2 glycoprotein alleviates palmitic acid-induced intracellular lipid accumulation in hepatocytes.". Mol Cell Endocrinol. 2017. PMID 27264075.