CACNB3

CACNB3
Dynodwyr
Cyfenwau	CACNB3, CAB3, CACNLB3, calcium voltage-gated channel auxiliary subunit beta 3
Dynodwyr allanol	OMIM: 601958 HomoloGene: 20187 GeneCards: CACNB3
Patrwm RNA pattern
	; ;
	Rhagor o gyfeiriadau
Ontoleg y genyn
Gweithrediad moleciwlaidd	• protein kinase binding; • voltage-gated ion channel activity; • voltage-gated calcium channel activity; • high voltage-gated calcium channel activity; • calcium channel activity; • GO:0001948, GO:0016582 protein binding; • calcium channel regulator activity;
Cydrannau o'r gell	• apical plasma membrane; • bilen; • cytosol; • Cellbilen; • voltage-gated calcium channel complex; • L-type voltage-gated calcium channel complex; • cytoplasm;
Prosesau biolegol	• membrane depolarization; • regulation of ion transmembrane transport; • cludo ïon; • regulation of voltage-gated calcium channel activity; • neuromuscular junction development; • calcium ion transmembrane transport; • calcium ion transport; • regulation of membrane repolarization during action potential; • calcium ion transport into cytosol; • protein localization to plasma membrane; • chemical synaptic transmission; • calcium ion transmembrane transport via high voltage-gated calcium channel; • detection of mechanical stimulus involved in sensory perception of pain; • positive regulation of protein targeting to membrane; • cellular response to oxygen-glucose deprivation; • negative regulation of voltage-gated calcium channel activity; • positive regulation of voltage-gated calcium channel activity; • positive regulation of high voltage-gated calcium channel activity; • regulation of membrane hyperpolarization; • negative regulation of detection of mechanical stimulus involved in sensory perception of touch; • positive regulation of excitatory postsynaptic potential; • T cell receptor signaling pathway; • cardiac conduction;
	Sources:Amigo / QuickGO
Orthologau
	784
	n/a
	ENSG00000167535
	n/a
	P54284
	n/a
	NM_000725; NM_001206915; NM_001206916; NM_001206917
	n/a
	NP_000716; NP_001193844; NP_001193845; NP_001193846
	n/a
	Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CACNB3 yw CACNB3 a elwir hefyd yn Calcium voltage-gated channel auxiliary subunit beta 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 12, band 12q13.12.^[2]

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CACNB3.

CAB3
CACNLB3

Llyfryddiaeth

"Beta subunit heterogeneity in N-type Ca2+ channels. ". J Biol Chem. 1996. PMID 8621722.
"Cloning, chromosomal location and functional expression of the human voltage-dependent calcium-channel beta 3 subunit. ". Eur J Biochem. 1994. PMID 8119293.
"Calmodulin-dependent gating of Ca(v)1.2 calcium channels in the absence of Ca(v)beta subunits. ". Proc Natl Acad Sci U S A. 2008. PMID 18535142.
"Gene structure of the murine calcium channel beta3 subunit, cDNA and characterization of alternative splicing and transcription products. ". Eur J Biochem. 1996. PMID 8617257.
"The structures of the human calcium channel alpha 1 subunit (CACNL1A2) and beta subunit (CACNLB3) genes.". Genomics. 1995. PMID 7557998.

Cyfeiriadau

[1] "Human PubMed Reference:".

[2] CACNB3 - Cronfa NCBI

[2]

[1]