CDC25B

Protein sy'n cael ei godio yn y corff dynol gan y genyn CDC25B yw CDC25B a elwir hefyd yn Cell division cycle 25B (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 20, band 20p13.

CDC25B
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1CWR, 1CWS, 1CWT, 1QB0, 1YM9, 1YMD, 1YMK, 1YML, 1YS0, 2A2K, 2IFD, 2IFV, 2UZQ, 3FQT, 3FQU, 4WH7, 4WH9
Dynodwyr
Cyfenwau	CDC25B, cell division cycle 25B
Dynodwyr allanol	OMIM: 116949 HomoloGene: 41451 GeneCards: CDC25B
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • protein tyrosine phosphatase activity • hydrolase activity • protein kinase binding • phosphoprotein phosphatase activity Cydrannau o'r gell • cytosol • centrosome • spindle pole • intracellular anatomical structure • microtubule organizing center • Cytosgerbwd • cnewyllyn cell • nucleoplasm • cytoplasm Prosesau biolegol • GO:0016576 protein dephosphorylation • positive regulation of mitotic cell cycle • Cellraniad • positive regulation of cytokinesis • protein phosphorylation • G2/M transition of mitotic cell cycle • oocyte maturation • positive regulation of cell population proliferation • cell cycle • female meiosis I • positive regulation of protein kinase activity • peptidyl-tyrosine dephosphorylation • positive regulation of cell cycle G2/M phase transition • GO:0007067 Mitosis • positive regulation of G2/M transition of mitotic cell cycle • positive regulation of G2/MI transition of meiotic cell cycle Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	994	n/a
Ensembl	ENSG00000101224	n/a
UniProt	P30305	n/a
RefSeq (mRNA)	NM_001287516 NM_001287517 NM_001287518 NM_001287519 NM_001287520 NM_001287522 NM_001287524 NM_004358 NM_021872 NM_021873 NM_021874 NM_212530	n/a
RefSeq (protein)	NP_001274445 NP_001274446 NP_001274447 NP_001274448 NP_001274449 NP_001274451 NP_001274453 NP_004349 NP_068658 NP_068659	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Llyfryddiaeth

• "Conformational flexibility of the complete catalytic domain of Cdc25B phosphatases. ". Proteins. 2016. PMID 27410025.
• "Solution NMR studies reveal no global flexibility in the catalytic domain of CDC25B. ". Proteins. 2014. PMID 24740794.
• "Targeting cell division cycle 25 homolog B to regulate influenza virus replication. ". J Virol. 2013. PMID 24109234.
• "Doxorubicin promotes transcriptional upregulation of Cdc25B in cancer cells by releasing Sp1 from the promoter. ". Oncogene. 2013. PMID 23160377.
• "Knockdown of Cdc25B in renal cell carcinoma is associated with decreased malignant features.". Asian Pac J Cancer Prev. 2012. PMID 22631674.