CREM

Protein sy'n cael ei godio yn y corff dynol gan y genyn CREM yw CREM a elwir hefyd yn cAMP-responsive element modulator (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 10, band 10p11.21.

CREM
Dynodwyr
Cyfenwau	CREM, CREM-2, ICER, hCREM-2, cAMP responsive element modulator
Dynodwyr allanol	OMIM: 123812 HomoloGene: 84591 GeneCards: CREM
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • DNA binding • cAMP response element binding protein binding • GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity • GO:0001948, GO:0016582 protein binding • RNA polymerase II transcription regulatory region sequence-specific DNA binding • GO:0001078, GO:0001214, GO:0001206 DNA-binding transcription repressor activity, RNA polymerase II-specific • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific Cydrannau o'r gell • cytoplasm • transcription regulator complex • cnewyllyn cell Prosesau biolegol • cell differentiation • GO:0009373 regulation of transcription, DNA-templated • glycosphingolipid metabolic process • proses rythmig • transcription, DNA-templated • fatty acid metabolic process • multicellular organism development • retinoic acid receptor signaling pathway • regulation of circadian rhythm • spermatogenesis • glucose metabolic process • GO:0003257, GO:0010735, GO:1901228, GO:1900622, GO:1904488 positive regulation of transcription by RNA polymerase II • GO:0072468 signal transduction • GO:1901227 negative regulation of transcription by RNA polymerase II Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1390	n/a
Ensembl	ENSG00000095794	n/a
UniProt	Q03060	n/a
RefSeq (mRNA)	NM_001267562 NM_001267563 NM_001267564 NM_001267565 NM_001267566 NM_001267567 NM_001267568 NM_001267569 NM_001267570 NM_001881 NM_181571 NM_182717 NM_182718 NM_182719 NM_182720 NM_182721 NM_182722 NM_182723 NM_182724 NM_182725 NM_182769 NM_182770 NM_182771 NM_182772 NM_182850 NM_182853 NM_183011 NM_183012 NM_183013 NM_183060 NM_001352445 NM_001352446 NM_001352465 NM_001352466 NM_001352467 NM_001394595 NM_001394598 NM_001394600 NM_001394602 NM_001394603 NM_001394605 NM_001394608 NM_001394610 NM_001394613 NM_001394614 NM_001394615 NM_001394616 NM_001394617 NM_001394618 NM_001394619 NM_001394620 NM_001394621 NM_001394622 NM_001394623 NM_001394625 NM_001394626 NM_001394627 NM_001394628 NM_001394629 NM_001394630 NM_001394631	n/a
RefSeq (protein)	NP_001254491 NP_001254492 NP_001254493 NP_001254494 NP_001254495 NP_001254496 NP_001254497 NP_001254498 NP_001254499 NP_001872 NP_853549 NP_874386 NP_874387 NP_874388 NP_874389 NP_874390 NP_874392 NP_874393 NP_877570 NP_877571 NP_877572 NP_877573 NP_898829 NP_898830 NP_898831 NP_898883 NP_001339374 NP_001339375 NP_001339394 NP_001339395 NP_001339396	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CREM.

• ICER
• CREM-2
• hCREM-2

Llyfryddiaeth

• "CREM variant rs17583959 conferred susceptibility to T1D risk in the Tunisian families. ". Immunol Lett. 2017. PMID 27840176.
• "Constitutive Expression of Inducible Cyclic Adenosine Monophosphate Early Repressor (ICER) in Cycling Quiescent Hematopoietic Cells: Implications for Aging Hematopoietic Stem Cells. ". Stem Cell Rev. 2017. PMID 27822872.
• "Cyclic AMP-Responsive Element Modulator α Polymorphisms Are Potential Genetic Risks for Systemic Lupus Erythematosus. ". J Immunol Res. 2015. PMID 26601115.
• "CREM variants rs4934540 and rs2295415 conferred susceptibility to nonobstructive azoospermia risk in the Chinese population. ". Biol Reprod. 2014. PMID 24943041.
• "Wide distribution of CREM immunoreactivity in adult and fetal human brain, with an increased expression in dentate gyrus neurons of Alzheimer's as compared to normal aging brains.". Amino Acids. 2013. PMID 24100545.