CYTH3

Protein sy'n cael ei godio yn y corff dynol gan y genyn CYTH3 yw CYTH3 a elwir hefyd yn Cytohesin 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 7, band 7p22.1.

CYTH3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4KAX
Dynodwyr
Cyfenwau	CYTH3, ARNO3, GRP1, PSCD3, cytohesin 3, cytohesin-3
Dynodwyr allanol	OMIM: 605081 HomoloGene: 3116 GeneCards: CYTH3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • phosphatidylinositol-3,4,5-trisphosphate binding • guanyl-nucleotide exchange factor activity • lipid binding Cydrannau o'r gell • cytoplasm • ruffle • extrinsic component of cytoplasmic side of plasma membrane • Cellbilen • bilen • Golgi membrane • cytosol • nucleoplasm • adherens junction • bicellular tight junction • cell junction Prosesau biolegol • regulation of ARF protein signal transduction • Golgi vesicle transport • positive regulation of cell adhesion • establishment of epithelial cell polarity Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	9265	n/a
Ensembl	ENSG00000008256	n/a
UniProt	O43739	n/a
RefSeq (mRNA)	NM_004227	n/a
RefSeq (protein)	NP_004218 NP_001354509 NP_001354510 NP_001354511	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CYTH3.

• GRP1
• ARNO3
• PSCD3
• cytohesin-3

Llyfryddiaeth

• "Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors. ". Proc Natl Acad Sci U S A. 2013. PMID 23940353.
• "Nerve growth factor- and epidermal growth factor-stimulated translocation of the ADP-ribosylation factor-exchange factor GRP1 to the plasma membrane of PC12 cells requires activation of phosphatidylinositol 3-kinase and the GRP1 pleckstrin homology domain. ". Biochem J. 1998. PMID 9742223.
• "Cytohesin-3 is upregulated in hepatocellular carcinoma and contributes to tumor growth and vascular invasion. ". Int J Clin Exp Pathol. 2014. PMID 24966920.
• "The GRP1 PH domain, like the AKT1 PH domain, possesses a sentry glutamate residue essential for specific targeting to plasma membrane PI(3,4,5)P(3). ". Biochemistry. 2011. PMID 21932773.
• "General receptor for phosphoinositides 1, a novel repressor of thyroid hormone receptor action that prevents deoxyribonucleic acid binding.". Mol Endocrinol. 2005. PMID 15878955.