DCTPP1

Protein sy'n cael ei godio yn y corff dynol gan y genyn DCTPP1 yw DCTPP1 a elwir hefyd yn DCTP pyrophosphatase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 16, band 16p11.2.

DCTPP1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2A3Q, 2OIE, 2OIG, 2Q4P
Dynodwyr
Cyfenwau	DCTPP1, RS21C6, XTP3TPA, CDA03, XTP3-transactivated gene A protein, dCTP pyrophosphatase 1
Dynodwyr allanol	OMIM: 615840 HomoloGene: 11329 GeneCards: DCTPP1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GO:0097382 pyrophosphatase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • magnesium ion binding • metal ion binding • identical protein binding • pyrimidine deoxyribonucleotide binding • dCTP diphosphatase activity • nucleoside-triphosphate diphosphatase activity Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • mitocondria Prosesau biolegol • protein homotetramerization • dCTP catabolic process • nucleoside triphosphate catabolic process • DNA protection • dTTP catabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	79077	n/a
Ensembl	ENSG00000179958	n/a
UniProt	Q9H773	n/a
RefSeq (mRNA)	NM_024096	n/a
RefSeq (protein)	NP_077001	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DCTPP1.

• CDA03
• RS21C6
• XTP3TPA

Llyfryddiaeth

• "The NTP pyrophosphatase DCTPP1 contributes to the homoeostasis and cleansing of the dNTP pool in human cells. ". Biochem J. 2014. PMID 24467396.
• "Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions. ". J Mol Biol. 2005. PMID 15740738.
• "Human dCTP pyrophosphatase 1 promotes breast cancer cell growth and stemness through the modulation on 5-methyl-dCTP metabolism and global hypomethylation. ". Oncogenesis. 2015. PMID 26075750.
• "dCTP pyrophosphohydrase exhibits nucleic accumulation in multiple carcinomas. ". Eur J Histochem. 2013. PMID 24085278.
• "Triptolide directly inhibits dCTP pyrophosphatase.". Chembiochem. 2011. PMID 21671327.