DDX6

Protein sy'n cael ei godio yn y corff dynol gan y genyn DDX6 yw DDX6 a elwir hefyd yn DEAD-box helicase 6 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q23.3.

DDX6
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1VEC, 2WAX, 2WAY, 4CRW, 4CT4, 4CT5, 5ANR
Dynodwyr
Cyfenwau	DDX6, HLR2, P54, RCK, DEAD-box helicase 6, IDDILF, Rck/p54
Dynodwyr allanol	OMIM: 600326 HomoloGene: 3238 GeneCards: DDX6
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • RNA helicase activity • nucleotide binding • GO:0008026 helicase activity • protein domain specific binding • GO:0001948, GO:0016582 protein binding • nucleic acid binding • hydrolase activity • ATP binding • RNA binding • cadherin binding Cydrannau o'r gell • cytoplasm • RISC complex • bilen • P-body • cytoplasmic stress granule • mitocondria • sperm annulus • P granule • outer dense fiber • GO:0035328 heterochromatin • cnewyllyn cell • cytosol • nucleolus • cytoplasmic ribonucleoprotein granule • chromatoid body • perinuclear region of cytoplasm • concave side of sperm head Prosesau biolegol • negative regulation of neuron differentiation • stem cell population maintenance • RNA secondary structure unwinding • P-body assembly • exonucleolytic catabolism of deadenylated mRNA • viral RNA genome packaging • regulation of translation • spermatogenesis • spermatid differentiation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1656	n/a
Ensembl	ENSG00000110367	n/a
UniProt	P26196	n/a
RefSeq (mRNA)	NM_001257191 NM_004397	n/a
RefSeq (protein)	NP_001244120 NP_004388	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DDX6.

• P54
• RCK
• HLR2

Llyfryddiaeth

• "Involvement of DDX6 gene in radio- and chemoresistance in glioblastoma. ". Int J Oncol. 2016. PMID 26783102.
• "DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways. ". Mol Cell. 2015. PMID 26412305.
• "P-body assembly requires DDX6 repression complexes rather than decay or Ataxin2/2L complexes. ". Mol Biol Cell. 2015. PMID 25995375.
• "Multiple binding of repressed mRNAs by the P-body protein Rck/p54. ". RNA. 2012. PMID 22836354.
• "Quantitative mass spectrometry of DENV-2 RNA-interacting proteins reveals that the DEAD-box RNA helicase DDX6 binds the DB1 and DB2 3' UTR structures.". RNA Biol. 2011. PMID 21957497.