DGUOK

Protein sy'n cael ei godio yn y corff dynol gan y genyn DGUOK yw DGUOK a elwir hefyd yn Deoxyguanosine kinase (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2p13.1.

DGUOK
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2OCP
Dynodwyr
Cyfenwau	DGUOK, deoxyguanosine kinase, MTDPS3, dGK, NCPH, PEOB4, NCPH1
Dynodwyr allanol	OMIM: 601465 HomoloGene: 8456 GeneCards: DGUOK
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • nucleoside kinase activity • deoxyguanosine kinase activity • kinase activity • ATP binding • deoxynucleoside kinase activity Cydrannau o'r gell • cytoplasm • cytosol • mitochondrial matrix • mitocondria • cnewyllyn cell Prosesau biolegol • negative regulation of neuron projection development • purine deoxyribonucleoside metabolic process • dGTP metabolic process • phosphorylation • purine-containing compound salvage • guanosine metabolic process • protein phosphorylation • nucleobase-containing compound metabolic process • nucleotide biosynthetic process • deoxyribonucleoside monophosphate biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1716	n/a
Ensembl	ENSG00000114956	n/a
UniProt	Q16854	n/a
RefSeq (mRNA)	NM_001929 NM_080915 NM_080916 NM_080917 NM_080918 NM_001318859 NM_001318860 NM_001318861 NM_001318862 NM_001318863	n/a
RefSeq (protein)	NP_001305788 NP_001305789 NP_001305790 NP_001305791 NP_001305792 NP_550438 NP_550440	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DGUOK.

• dGK
• NCPH
• PEOB4
• MTDPS3

Llyfryddiaeth

• "[Clinical features and DGUOK mutations of an infant with mitochondrial DNA depletion syndrome]. ". Zhongguo Dang Dai Er Ke Za Zhi. 2016. PMID 27324545.
• "Recurrent recessive mutation in deoxyguanosine kinase causes idiopathic noncirrhotic portal hypertension. ". Hepatology. 2016. PMID 26874653.
• "Next-generation sequencing reveals DGUOK mutations in adult patients with mitochondrial DNA multiple deletions. ". Brain. 2012. PMID 23043144.
• "Post mortem identification of deoxyguanosine kinase (DGUOK) gene mutations combined with impaired glucose homeostasis and iron overload features in four infants with severe progressive liver failure. ". J Appl Genet. 2011. PMID 21107780.
• Deoxyguanosine Kinase Deficiency. 1993. PMID 20301766.