DSP

Protein sy'n cael ei godio yn y corff dynol gan y genyn DSP yw DSP a elwir hefyd yn Desmoplakin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6p24.3.

DSP
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 3R6N, 1LM5, 1LM7, 5DZZ
Dynodwyr
Cyfenwau	DSP, DCWHKTA, DP, DPI, DPII, desmoplakin
Dynodwyr allanol	OMIM: 125647 HomoloGene: 37922 GeneCards: DSP
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • protein-macromolecule adaptor activity • scaffold protein binding • structural molecule activity • structural constituent of cytoskeleton • GO:0001948, GO:0016582 protein binding • cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication • cell adhesion molecule binding • protein kinase C binding • RNA binding Cydrannau o'r gell • cytoplasm • bilen • intercalated disc • cell-cell junction • Cellbilen • desmosome • cell junction • basolateral plasma membrane • fascia adherens • extracellular exosome • Cytosgerbwd • intermediate filament • cnewyllyn cell • GO:0005578 extracellular matrix • cornified envelope • ficolin-1-rich granule membrane Prosesau biolegol • intermediate filament organization • desmosome organization • ventricular compact myocardium morphogenesis • wound healing • bundle of His cell-Purkinje myocyte adhesion involved in cell communication • keratinocyte differentiation • GO:0051357, GO:0051358, GO:0051359 peptide cross-linking • protein localization to adherens junction • epidermis development • intermediate filament cytoskeleton organization • adherens junction organization • regulation of heart rate by cardiac conduction • regulation of ventricular cardiac muscle cell action potential • skin development • keratinization • neutrophil degranulation • cornification • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1832	n/a
Ensembl	ENSG00000096696	n/a
UniProt	P15924	n/a
RefSeq (mRNA)	NM_001008844 NM_004415 NM_001319034	n/a
RefSeq (protein)	NP_001008844 NP_001305963 NP_004406	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DSP.

• DP
• DCWHKTA

Llyfryddiaeth

• "Novel truncating desmoplakin mutation as a potential cause of sudden cardiac death in a family. ". Pol Arch Med Wewn. 2016. PMID 27698334.
• "Progressive cardiac conduction disease associated with a DSP gene mutation. ". Int J Cardiol. 2016. PMID 27166992.
• "Desmoplakin Variants Are Associated with Idiopathic Pulmonary Fibrosis. ". Am J Respir Crit Care Med. 2016. PMID 26669357.
• "Dominant de novo DSP mutations cause erythrokeratodermia-cardiomyopathy syndrome. ". Hum Mol Genet. 2016. PMID 26604139.
• "Identification of rare variants of DSP gene in sudden unexplained nocturnal death syndrome in the southern Chinese Han population.". Int J Legal Med. 2016. PMID 26585738.