DVL3

Protein sy'n cael ei godio yn y corff dynol gan y genyn DVL3 yw DVL3 a elwir hefyd yn Dishevelled segment polarity protein 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 3, band 3q27.1.

DVL3
Dynodwyr
Cyfenwau	DVL3, DRS3, dishevelled segment polarity protein 3
Dynodwyr allanol	OMIM: 601368 HomoloGene: 20928 GeneCards: DVL3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • beta-catenin binding • GO:0005110 frizzled binding • protease binding • GO:0001948, GO:0016582 protein binding • protein heterodimerization activity • signaling receptor binding Cydrannau o'r gell • cytoplasm • cytosol Prosesau biolegol • positive regulation of protein phosphorylation • GO:0007243 intracellular signal transduction • positive regulation of JUN kinase activity • protein stabilization • Wnt signaling pathway • GO:0060469, GO:0009371 positive regulation of transcription, DNA-templated • multicellular organism development • GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity • negative regulation of canonical Wnt signaling pathway • beta-catenin destruction complex disassembly • non-canonical Wnt signaling pathway • non-canonical Wnt signaling pathway via JNK cascade • canonical Wnt signaling pathway • Wnt signaling pathway, planar cell polarity pathway • planar cell polarity pathway involved in neural tube closure • positive regulation of neuron projection arborization Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1857	n/a
Ensembl	ENSG00000161202	n/a
UniProt	Q92997	n/a
RefSeq (mRNA)	NM_004423	n/a
RefSeq (protein)	NP_004414	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn DVL3.

• DRS3

Llyfryddiaeth

• "Dishevelled segment polarity protein 3 (DVL3): a novel and easily applicable recurrence predictor in localised prostate adenocarcinoma. ". BJU Int. 2017. PMID 28107606.
• "Dsh homolog DVL3 mediates resistance to IGFIR inhibition by regulating IGF-RAS signaling. ". Cancer Res. 2014. PMID 25168481.
• "AMPK activators suppress cervical cancer cell growth through inhibition of DVL3 mediated Wnt/β-catenin signaling activity. ". PLoS One. 2013. PMID 23301094.
• "Delicate analysis of post-translational modifications on Dishevelled 3. ". J Proteome Res. 2012. PMID 22612246.
• "ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size.". PLoS Genet. 2016. PMID 27008544.