EFNB2

Protein sy'n cael ei godio yn y corff dynol gan y genyn EFNB2 yw EFNB2 a elwir hefyd yn Ephrin B2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 13, band 13q33.3.

EFNB2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HLE, 2I85, 2VSK, 2VSM, 2WO2, 3GXU, 4UF7
Dynodwyr
Cyfenwau	EFNB2, EPLG5, HTKL, Htk-L, LERK5, ephrin B2
Dynodwyr allanol	OMIM: 600527 HomoloGene: 3019 GeneCards: EFNB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • virus receptor activity • GO:0001948, GO:0016582 protein binding • signaling receptor binding • ephrin receptor binding • protein tyrosine kinase activity Cydrannau o'r gell • integral component of membrane • bilen • focal adhesion • Cellbilen • integral component of plasma membrane • Schaffer collateral - CA1 synapse • glutamatergic synapse • integral component of presynaptic membrane • integral component of postsynaptic density membrane Prosesau biolegol • cell differentiation • blood vessel morphogenesis • negative regulation of keratinocyte proliferation • regulation of chemotaxis • cell-cell signaling • anatomical structure morphogenesis • T cell costimulation • lymph vessel development • nervous system development • cell migration involved in sprouting angiogenesis • multicellular organism development • cell adhesion • nephric duct morphogenesis • angiogenesis • animal organ morphogenesis • viral entry into host cell • positive regulation of cardiac muscle cell differentiation • GO:0022415 viral process • venous blood vessel morphogenesis • positive regulation of aorta morphogenesis • positive regulation of cell population proliferation • ephrin receptor signaling pathway • axon guidance • negative regulation of neuron projection development • peptidyl-tyrosine phosphorylation • presynapse assembly • regulation of postsynaptic membrane neurotransmitter receptor levels • regulation of postsynaptic neurotransmitter receptor internalization • positive regulation of neuron death Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	1948	n/a
Ensembl	ENSG00000125266	n/a
UniProt	P52799	n/a
RefSeq (mRNA)	NM_004093 NM_001372056 NM_001372057 NM_001372058	n/a
RefSeq (protein)	NP_004084 NP_001358985 NP_001358986 NP_001358987	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn EFNB2.

• HTKL
• EPLG5
• Htk-L
• LERK5

Llyfryddiaeth

• "Ephrin-B2 reverse signaling regulates progression and lymph node metastasis of oral squamous cell carcinoma. ". PLoS One. 2017. PMID 29190834.
• "Ephrin-B2 overexpression predicts for poor prognosis and response to therapy in solid tumors. ". Mol Carcinog. 2017. PMID 27649287.
• "EphrinB2 Stabilizes Vascularlike Structures Generated by Endothelial Cells and Stem Cells from Apical Papilla. ". J Endod. 2016. PMID 27451120.
• "EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells. ". Elife. 2016. PMID 27350048.
• "DNA damage-induced ephrin-B2 reverse signaling promotes chemoresistance and drives EMT in colorectal carcinoma harboring mutant p53.". Cell Death Differ. 2016. PMID 26494468.