F11

Protein sy'n cael ei godio yn y corff dynol gan y genyn F11 yw F11 a elwir hefyd yn Coagulation factor XI (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 4, band 4q35.2.

F11
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1XX9, 1XXD, 1XXF, 1ZHM, 1ZHP, 1ZHR, 1ZJD, 1ZLR, 1ZMJ, 1ZML, 1ZMN, 1ZOM, 1ZPB, 1ZPC, 1ZPZ, 1ZRK, 1ZSJ, 1ZSK, 1ZSL, 1ZTJ, 1ZTK, 1ZTL, 2F83, 2FDA, 2J8J, 2J8L, 3BG8, 3SOR, 3SOS, 4CR5, 4CR9, 4CRA, 4CRB, 4CRC, 4CRD, 4CRE, 4CRF, 4CRG, 4NA7, 4NA8, 4TY6, 4TY7, 4WXI, 4X6M, 4X6N, 4X6O, 4X6P, 4Y8X, 4Y8Y, 4Y8Z, 4D7F, 5E2O, 5E2P, 4D76, 4D7G, 5EXL, 5I25, 5EXM, 5EOD, 5EXN, 5EOK
Dynodwyr
Cyfenwau	F11, FXI, coagulation factor XI, PTA, factor XI
Dynodwyr allanol	OMIM: 264900 HomoloGene: 86654 GeneCards: F11
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • serine-type aminopeptidase activity • GO:0070122 peptidase activity • heparin binding • serine-type endopeptidase activity • serine-type peptidase activity • GO:0001948, GO:0016582 protein binding • hydrolase activity • identical protein binding Cydrannau o'r gell • extracellular region • Cellbilen • extracellular exosome • bilen • extracellular space Prosesau biolegol • hemostasis • blood coagulation, intrinsic pathway • plasminogen activation • regulation of blood coagulation • proteolysis • positive regulation of fibrinolysis • blood coagulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2160	n/a
Ensembl	ENSG00000088926	n/a
UniProt	P03951	n/a
RefSeq (mRNA)	NM_000128 NM_019559 NM_001354804	n/a
RefSeq (protein)	NP_000119 NP_001341733	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn F11.

• FXI
• PTA

Llyfryddiaeth

• "Exploring the global landscape of genetic variation in coagulation factor XI deficiency. ". Blood. 2017. PMID 28615222.
• "Next generation sequencing to dissect the genetic architecture of KNG1 and F11 loci using factor XI levels as an intermediate phenotype of thrombosis. ". PLoS One. 2017. PMID 28445521.
• "Clinical and molecular epidemiology of factor XI deficiency in India. ". Thromb Res. 2016. PMID 27710856.
• "F11 rs2289252T and rs2036914C Polymorphisms Increase the Activity of Factor XI in Post-trauma Patients with Fractures Despite Thromboprophylaxis. ". Orthop Surg. 2016. PMID 27627722.
• "Genetic risk factors for venous thrombosis in women using combined oral contraceptives: update of the PILGRIM study.". Clin Genet. 2017. PMID 27414984.