FBLIM1

Protein sy'n cael ei godio yn y corff dynol gan y genyn FBLIM1 yw FBLIM1 a elwir hefyd yn Filamin-binding LIM protein 1 a Filamin binding LIM protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1p36.21.

FBLIM1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2K9U, 2W0P, 4P3W
Dynodwyr
Cyfenwau	FBLIM1, CAL, FBLP-1, FBLP1, filamin binding LIM protein 1
Dynodwyr allanol	OMIM: 607747 HomoloGene: 56774 GeneCards: FBLIM1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • filamin binding • GO:0001948, GO:0016582 protein binding • metal ion binding Cydrannau o'r gell • cytoplasm • cytosol • cell cortex • Cytosgerbwd • stress fiber • focal adhesion • fibrillar center • cell junction Prosesau biolegol • regulation of integrin activation • cell adhesion • cell junction assembly • regulation of cell shape • cell-cell adhesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	54751	n/a
Ensembl	ENSG00000162458	n/a
UniProt	Q8WUP2	n/a
RefSeq (mRNA)	NM_001024215 NM_001024216 NM_017556 NM_001350151	n/a
RefSeq (protein)	NP_001019386 NP_001019387 NP_060026 NP_001337080	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FBLIM1.

• CAL
• FBLP1
• FBLP-1

Llyfryddiaeth

• "Increased cytoplasmic level of migfilin is associated with higher grades of human leiomyosarcoma. ". Histopathology. 2007. PMID 17711449.
• "Migfilin and its binding partners: from cell biology to human diseases. ". J Cell Sci. 2005. PMID 15701922.
• "Recessive coding and regulatory mutations in FBLIM1 underlie the pathogenesis of chronic recurrent multifocal osteomyelitis (CRMO). ". PLoS One. 2017. PMID 28301468.
• "Migfilin's elimination from osteoarthritic chondrocytes further promotes the osteoarthritic phenotype via β-catenin upregulation. ". Biochem Biophys Res Commun. 2013. PMID 23237804.
• "Migfilin and filamin as regulators of integrin activation in endothelial cells and neutrophils.". PLoS One. 2011. PMID 22043318.