Protein sy'n cael ei godio yn y corff dynol gan y genyn FCGRT yw FCGRT a elwir hefyd yn IgG receptor FcRn large subunit p51 a Fc fragment of IgG receptor and transporter (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 19, band 19q13.33.[2]

FCGRT
Strwythurau
PDBHuman UniProt search: PDBe RCSB
Dynodwyr
CyfenwauFCGRT, FCRN, alpha-chain, Fc fragment of IgG receptor and transporter, FcgammaRn, Fc gamma receptor and transporter
Dynodwyr allanolOMIM: 601437 HomoloGene: 3030 GeneCards: FCGRT
Patrwm RNA pattern
Rhagor o gyfeiriadau
Orthologau
SpeciesBod dynolLlygoden
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001136019
NM_004107

n/a

RefSeq (protein)

NP_001129491
NP_004098

n/a

Lleoliad (UCSC)n/an/a
PubMed search[1]n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

golygu

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCGRT.

  • FCRN
  • alpha-chain

Llyfryddiaeth

golygu
  • "Associations between an IgG3 polymorphism in the binding domain for FcRn, transplacental transfer of malaria-specific IgG3, and protection against Plasmodium falciparum malaria during infancy: A birth cohort study in Benin. ". PLoS Med. 2017. PMID 28991911.
  • "The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa. ". J Immunol. 2017. PMID 28760885.
  • "Correlation of FCGRT genomic structure with serum immunoglobulin, albumin and farletuzumab pharmacokinetics in patients with first relapsed ovarian cancer. ". Genomics. 2017. PMID 28450240.
  • "The expression and function of the neonatal Fc receptor in thyrocytes of Hashimoto's thyroiditis. ". Int Immunopharmacol. 2017. PMID 28081504.
  • "Neonatal Fc receptor FcRn is involved in intracellular transport of the Fc fusion protein aflibercept and its transition through retinal endothelial cells.". Exp Eye Res. 2017. PMID 27836572.

Cyfeiriadau

golygu
  1. "Human PubMed Reference:".
  2. FCGRT - Cronfa NCBI