FCN1

Protein sy'n cael ei godio yn y corff dynol gan y genyn FCN1 yw FCN1 a elwir hefyd yn Ficolin 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 9, band 9q34.3.

FCN1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2D39, 2JHH, 2JHI, 2JHK, 2JHL, 2JHM, 2WNP
Dynodwyr
Cyfenwau	FCN1, FCNM, ficolin 1
Dynodwyr allanol	OMIM: 601252 HomoloGene: 1518 GeneCards: FCN1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • sialic acid binding • GO:0001948, GO:0016582 protein binding • G protein-coupled receptor binding • metal ion binding • carbohydrate binding • GO:0008329 pattern recognition receptor activity • serine-type endopeptidase activity • carbohydrate derivative binding Cydrannau o'r gell • extracellular region • Cellbilen • collagen • extrinsic component of external side of plasma membrane • bilen • secretory granule lumen • ficolin-1-rich granule lumen • collagen-containing extracellular matrix Prosesau biolegol • complement activation, lectin pathway • complement activation • G protein-coupled receptor signaling pathway • recognition of apoptotic cell • protein localization to cell surface • cell surface pattern recognition receptor signaling pathway • immune system process • proteolysis • innate immune response • neutrophil degranulation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2219	n/a
Ensembl	ENSG00000085265	n/a
UniProt	O00602	n/a
RefSeq (mRNA)	NM_002003	n/a
RefSeq (protein)	NP_001994	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FCN1.

• FCNM

Llyfryddiaeth

• "Polymorphism in ficolin-1 (FCN1) gene is associated with an earlier onset of type 1 diabetes mellitus in children and adolescents from northeast Brazil. ". J Genet. 2016. PMID 27994205.
• "Enhancement of Ebola Virus Infection via Ficolin-1 Interaction with the Mucin Domain of GP Glycoprotein. ". J Virol. 2016. PMID 26984723.
• "Early ficolin-1 is a sensitive prognostic marker for functional outcome in ischemic stroke. ". J Neuroinflammation. 2016. PMID 26792363.
• "The pattern recognition molecule ficolin-1 exhibits differential binding to lymphocyte subsets, providing a novel link between innate and adaptive immunity. ". Mol Immunol. 2014. PMID 24161415.
• "M-ficolin levels reflect disease activity and predict remission in early rheumatoid arthritis.". Arthritis Rheum. 2013. PMID 24022747.