FKBP5

Protein sy'n cael ei godio yn y corff dynol gan y genyn FKBP5 yw FKBP5 a elwir hefyd yn FK506 binding protein 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.31.

FKBP5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1KT0, 3O5D, 3O5E, 3O5F, 3O5G, 3O5I, 3O5J, 3O5K, 3O5L, 3O5M, 3O5O, 3O5P, 3O5Q, 3O5R, 4DRH, 4DRI, 4DRK, 4DRM, 4DRN, 4DRO, 4DRP, 4DRQ, 4JFI, 4JFJ, 4JFK, 4JFL, 4JFM, 4R0X, 4TW6, 4TW7, 4TX0, 4W9O, 4W9P, 4W9Q, 5DIT, 5DIU, 5BXJ, 5DIV
Dynodwyr
Cyfenwau	FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10, FK506 binding protein 5, FKBP prolyl isomerase 5
Dynodwyr allanol	OMIM: 602623 HomoloGene: 3038 GeneCards: FKBP5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • isomerase activity • GO:0001948, GO:0016582 protein binding • heat shock protein binding • peptidyl-prolyl cis-trans isomerase activity • FK506 binding Cydrannau o'r gell • extracellular exosome • bilen • cnewyllyn cell • nucleoplasm • cytoplasm • cytosol Prosesau biolegol • protein peptidyl-prolyl isomerization • chaperone-mediated protein folding • protein folding • response to bacterium Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2289	n/a
Ensembl	ENSG00000096060	n/a
UniProt	Q13451	n/a
RefSeq (mRNA)	NM_004117 NM_001145775 NM_001145776 NM_001145777	n/a
RefSeq (protein)	NP_001139247 NP_001139248 NP_001139249 NP_004108	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FKBP5.

• P54
• AIG6
• FKBP51
• FKBP54
• PPIase
• Ptg-10

Llyfryddiaeth

• "Silencing of FKBP51 alleviates the mechanical pain threshold, inhibits DRG inflammatory factors and pain mediators through the NF-kappaB signaling pathway. ". Gene. 2017. PMID 28629826.
• "Methylation matters: FK506 binding protein 51 (FKBP5) methylation moderates the associations of FKBP5 genotype and resistant attachment with stress regulation. ". Dev Psychopathol. 2017. PMID 28401840.
• "FKBP5 genotype and early life stress exposure predict neurobehavioral outcomes for preterm infants. ". Dev Psychobiol. 2017. PMID 28247564.
• "FKBP51 Immunohistochemical Expression: A New Prognostic Biomarker for OSCC?". Int J Mol Sci. 2017. PMID 28218707.
• "FKBP51 regulates cell motility and invasion via RhoA signaling.". Cancer Sci. 2017. PMID 28032931.