FTH1

Protein sy'n cael ei godio yn y corff dynol gan y genyn FTH1 yw FTH1 a elwir hefyd yn Ferritin (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 11, band 11q12.3.

FTH1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1FHA, 2CEI, 2CHI, 2CIH, 2CLU, 2CN6, 2CN7, 2FHA, 2IU2, 2Z6M, 3AJO, 3AJP, 3AJQ, 3ERZ, 3ES3, 4DYX, 4DYY, 4DYZ, 4DZ0, 4OYN, 4Y08, 4YKH, 4ZJK, 5CMQ, 5CMR
Dynodwyr
Cyfenwau	FTH1, FHC, FTH, FTHL6, HFE5, PIG15, PLIF, ferritin, heavy polypeptide 1, ferritin heavy chain 1
Dynodwyr allanol	OMIM: 134770 HomoloGene: 74295 GeneCards: FTH1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • ferric iron binding • metal ion binding • ferroxidase activity • GO:0001948, GO:0016582 protein binding • oxidoreductase activity • iron ion binding • ferrous iron binding • identical protein binding Cydrannau o'r gell • cytosol • intracellular ferritin complex • extracellular exosome • cnewyllyn cell • extracellular region • autolysosome • tertiary granule lumen • ficolin-1-rich granule lumen • cytoplasm Prosesau biolegol • intracellular sequestering of iron ion • iron ion transport • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • negative regulation of fibroblast proliferation • negative regulation of cell population proliferation • cellular iron ion homeostasis • neutrophil degranulation • negative regulation of necrotic cell death Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2495	n/a
Ensembl	ENSG00000167996	n/a
UniProt	P02794	n/a
RefSeq (mRNA)	NM_002032	n/a
RefSeq (protein)	NP_002023	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FTH1.

• FHC
• FTH
• HFE5
• PLIF
• FTHL6
• PIG15

Llyfryddiaeth

• "The CD68(+)/H-ferritin(+) cells colonize the lymph nodes of the patients with adult onset Still's disease and are associated with increased extracellular level of H-ferritin in the same tissue: correlation with disease severity and implication for pathogenesis. ". Clin Exp Immunol. 2016. PMID 26540556.
• "Iron binding to human heavy-chain ferritin. ". Acta Crystallogr D Biol Crystallogr. 2015. PMID 26327381.
• "Noninvasive MRI and multilineage differentiation capability of ferritin-transduced human mesenchymal stem cells. ". NMR Biomed. 2015. PMID 25448225.
• "Significance of ferritin expression in formation of malignant phenotype of human breast cancer cells. ". Exp Oncol. 2014. PMID 25265351.
• "Elevated serum ferritin levels in patients with hematologic malignancies.". Asian Pac J Cancer Prev. 2014. PMID 25124580.