FYB1

Protein sy'n cael ei godio yn y corff dynol gan y genyn FYB1 yw FYB1 a elwir hefyd yn FYN binding protein 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5p13.1.

FYB1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1RI9, 2GTJ, 2GTO
Dynodwyr
Cyfenwau	FYB1, ADAP, PRO0823, SLAP-130, SLAP130, FYB, FYN binding protein, THC3, FYN binding protein 1
Dynodwyr allanol	OMIM: 602731 HomoloGene: 22664 GeneCards: FYB1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signaling receptor binding • GO:0001948, GO:0016582 protein binding • lipid binding • GO:0032403 protein-containing complex binding Cydrannau o'r gell • cytoplasm • cytosol • cnewyllyn cell • actin cytoskeleton • Cellbilen • cell junction Prosesau biolegol • protein phosphorylation • GO:0007243 intracellular signal transduction • protein localization to plasma membrane • T cell receptor signaling pathway • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • GO:0072468 signal transduction • NLS-bearing protein import into nucleus • GO:0022610 proses fiolegol • integrin-mediated signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2533	n/a
Ensembl	ENSG00000082074	n/a
UniProt	O15117	n/a
RefSeq (mRNA)	NM_001243093 NM_001465 NM_199335 NM_001349333 NM_018594	n/a
RefSeq (protein)	NP_001230022 NP_001456 NP_955367 NP_001336262 NP_061064	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn FYB1.

• FYB
• ADAP
• THC3
• PRO0823
• SLAP130
• SLAP-130

Llyfryddiaeth

• "Tyrosine-phosphorylation of the scaffold protein ADAP and its role in T cell signaling. ". Expert Rev Proteomics. 2016. PMID 27258783.
• "Deleterious mutation in the FYB gene is associated with congenital autosomal recessive small-platelet thrombocytopenia. ". J Thromb Haemost. 2015. PMID 25876182.
• "Short Communication FYB polymorphisms in Brazilian patients with type I diabetes mellitus and autoimmune polyglandular syndrome type III. ". Genet Mol Res. 2015. PMID 25729932.
• "Recessive thrombocytopenia likely due to a homozygous pathogenic variant in the FYB gene: case report. ". BMC Med Genet. 2014. PMID 25516138.
• "Immune adaptor ADAP in T cells regulates HIV-1 transcription and cell-cell viral spread via different co-receptors.". Retrovirology. 2013. PMID 24047317.