GCG

Protein sy'n cael ei godio yn y corff dynol gan y genyn GCG yw GCG a elwir hefyd yn Glucagon (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 2, band 2q24.2.

GCG
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1BH0, 1NAU, 2G49, 2M5P, 2M5Q,%%s4ZGM, 4APD, 3IOL, 1D0R,%%s2L64, 2L63
Dynodwyr
Cyfenwau	GCG, GLP1, glucagon, GRPP, GLP-1, GLP2
Dynodwyr allanol	OMIM: 138030 HomoloGene: 136497 GeneCards: GCG
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0001948, GO:0016582 protein binding • identical protein binding • hormone activity • glucagon receptor binding • signaling receptor binding Cydrannau o'r gell • cytoplasm • endoplasmic reticulum lumen • extracellular region • secretory granule lumen • extracellular space Prosesau biolegol • negative regulation of execution phase of apoptosis • G protein-coupled receptor signaling pathway • regulation of insulin secretion • cellular response to glucagon stimulus • positive regulation of peptidyl-serine phosphorylation • positive regulation of calcium ion import • positive regulation of histone H3-K4 methylation • positive regulation of peptidyl-threonine phosphorylation • feeding behavior • positive regulation of ERK1 and ERK2 cascade • positive regulation of protein binding • cell population proliferation • GO:0072468 signal transduction • positive regulation of protein kinase activity • adenylate cyclase-modulating G protein-coupled receptor signaling pathway • protein kinase A signaling • positive regulation of insulin secretion involved in cellular response to glucose stimulus • response to starvation • negative regulation of apoptotic process • regulation of signaling receptor activity • adenylate cyclase-activating G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2641	n/a
Ensembl	ENSG00000115263	n/a
UniProt	P01275	n/a
RefSeq (mRNA)	NM_002054	n/a
RefSeq (protein)	NP_002045	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GCG.

• GLP1
• GLP2
• GRPP
• GLP-1

Llyfryddiaeth

• "GLP-1 response to sequential mixed meals: influence of insulin resistance. ". Clin Sci (Lond). 2017. PMID 29097626.
• "The Role of GLP-1 in the Metabolic Success of Bariatric Surgery. ". Endocrinology. 2017. PMID 29040429.
• "Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling. ". J Clin Invest. 2017. PMID 28920919.
• "Glucagon-like Peptide-1 Analogues Inhibit Proliferation and Increase Apoptosis of Human Prostate Cancer Cells in vitro. ". Exp Clin Endocrinol Diabetes. 2017. PMID 28008585.
• "Influence of glucagon-like peptide 2 on energy homeostasis.". Peptides. 2016. PMID 27664588.