GFRA3

Protein sy'n cael ei godio yn y corff dynol gan y genyn GFRA3 yw GFRA3 a elwir hefyd yn GDNF family receptor alpha 3 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 5, band 5q31.2.

GFRA3
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2GH0
Dynodwyr
Cyfenwau	GFRA3, GDNFR3, GDNF family receptor alpha 3
Dynodwyr allanol	OMIM: 605710 HomoloGene: 1146 GeneCards: GFRA3
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • signaling receptor binding • axon guidance receptor activity • GO:0001948, GO:0016582 protein binding • signaling receptor activity Cydrannau o'r gell • bilen • anchored component of membrane • external side of plasma membrane • extrinsic component of membrane • Cellbilen • cytosol • receptor complex Prosesau biolegol • neuron development • neuron migration • peripheral nervous system development • sympathetic nervous system development • GO:0072468 signal transduction • nervous system development • MAPK cascade • axon guidance Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2676	n/a
Ensembl	ENSG00000146013	n/a
UniProt	O60609	n/a
RefSeq (mRNA)	NM_001496	n/a
RefSeq (protein)	NP_001487	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GFRA3.

• GDNFR3

Llyfryddiaeth

• "GFRA3 promoter methylation may be associated with decreased postoperative survival in gastric cancer. ". BMC Cancer. 2016. PMID 26984265.
• "Characterisation of the human GFRalpha-3 locus and investigation of the gene in Hirschsprung disease. ". J Med Genet. 2000. PMID 10978357.
• "Molecular cloning, expression and tissue distribution of glial-cell-line-derived neurotrophic factor family receptor alpha-3 (GFRalpha-3). ". Eur J Biochem. 1998. PMID 9490034.
• "Craniopharyngiomas express embryonic stem cell markers (SOX2, OCT4, KLF4, and SOX9) as pituitary stem cells but do not coexpress RET/GFRA3 receptors. ". J Clin Endocrinol Metab. 2012. PMID 22031517.
• "Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors.". Structure. 2006. PMID 16765900.