GNB2

Protein sy'n cael ei godio yn y corff dynol gan y genyn GNB2 yw GNB2 a elwir hefyd yn Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 a G protein subunit beta 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 7, band 7q22.1.

GNB2
Dynodwyr
Cyfenwau	GNB2, G protein subunit beta 2, SSS4, SSS4; NEDHYDF, HG2C1
Dynodwyr allanol	OMIM: 139390 HomoloGene: 68451 GeneCards: GNB2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • GO:0032403 protein-containing complex binding • calcium channel regulator activity • signal transducer activity • GO:0001948, GO:0016582 protein binding • GO:0006184 GTPase activity • GTPase binding Cydrannau o'r gell • cytoplasm • cell body • fesigl • bilen • focal adhesion • myelin sheath • Cellbilen • lysosomal membrane • perinuclear region of cytoplasm • extracellular exosome • cytosol • extracellular space • GO:0009327 protein-containing complex Prosesau biolegol • G protein-coupled receptor signaling pathway • cellular response to glucagon stimulus • GO:0072468 signal transduction • protein folding • regulation of molecular function Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	2783	n/a
Ensembl	ENSG00000172354	n/a
UniProt	P62879	n/a
RefSeq (mRNA)	NM_005273	n/a
RefSeq (protein)	NP_005264	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Llyfryddiaeth

• "A Mutation in the G-Protein Gene GNB2Causes Familial Sinus Node and Atrioventricular Conduction Dysfunction. ". Circ Res. 2017. PMID 28219978.
• "Direct selection: a method for the isolation of cDNAs encoded by large genomic regions. ". Proc Natl Acad Sci U S A. 1991. PMID 1946378.
• "Mutations in G protein β subunits promote transformation and kinase inhibitor resistance. ". Nat Med. 2015. PMID 25485910.
• "Identification of cellular proteins interacting with influenza A virus PB1-F2 protein. ". Acta Virol. 2012. PMID 23043599.
• "The molecular basis for T-type Ca2+ channel inhibition by G protein beta2gamma2 subunits.". Proc Natl Acad Sci U S A. 2006. PMID 16973746.