GTF2H5

Protein sy'n cael ei godio yn y corff dynol gan y genyn GTF2H5 yw GTF2H5 a elwir hefyd yn General transcription factor IIH subunit 5 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 6, band 6q25.3.

GTF2H5
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YDL, 2JNJ, 5IY8, 5IY6, 5IY7, 5IVW, 5IY9
Dynodwyr
Cyfenwau	GTF2H5, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2, TTD3, general transcription factor IIH subunit 5
Dynodwyr allanol	OMIM: 608780 HomoloGene: 45635 GeneCards: GTF2H5
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • rDNA binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • nucleoplasm • nucleolus • GO:0000441 transcription factor TFIIH core complex • cnewyllyn cell • transcription factor TFIID complex • transcription factor TFIIH holo complex Prosesau biolegol • termination of RNA polymerase I transcription • GO:0009373 regulation of transcription, DNA-templated • transcription initiation from RNA polymerase I promoter • transcription elongation from RNA polymerase II promoter • 7-methylguanosine mRNA capping • transcription by RNA polymerase II • transcription, DNA-templated • cellular response to DNA damage stimulus • global genome nucleotide-excision repair • cellular response to gamma radiation • rRNA processing • transcription-coupled nucleotide-excision repair • transcription initiation from RNA polymerase II promoter • nucleotide-excision repair, DNA incision • nucleotide-excision repair, preincision complex assembly • nucleotide-excision repair • nucleotide-excision repair, DNA incision, 5'-to lesion • GO:0100026 DNA repair • nucleotide-excision repair, preincision complex stabilization • GO:0001183 transcription elongation from RNA polymerase I promoter • phosphorylation of RNA polymerase II C-terminal domain • nucleotide-excision repair, DNA duplex unwinding • nucleotide-excision repair, DNA incision, 3'-to lesion Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	404672	n/a
Ensembl	ENSG00000272047	n/a
UniProt	Q6ZYL4	n/a
RefSeq (mRNA)	NM_207118	n/a
RefSeq (protein)	NP_997001	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn GTF2H5.

• TTD
• TFB5
• TTD3
• TTDA
• TFIIH
• TTD-A
• TGF2H5
• C6orf175
• bA120J8.2

Llyfryddiaeth

• "p8/TTD-A as a repair-specific TFIIH subunit. ". Mol Cell. 2006. PMID 16427011.
• "Molecular evolution of the second ancient human mariner transposon, Hsmar2, illustrates patterns of neutral evolution in the human genome lineage. ". Gene. 1997. PMID 9461396.
• "The NER-related gene GTF2H5 predicts survival in high-grade serous ovarian cancer patients. ". J Gynecol Oncol. 2016. PMID 26463438.
• "In vivo interactions of TTDA mutant proteins within TFIIH. ". J Cell Sci. 2013. PMID 23729738.
• "Solution structure and self-association properties of the p8 TFIIH subunit responsible for trichothiodystrophy.". J Mol Biol. 2007. PMID 17350038.