HLA-DMA

Protein sy'n cael ei godio yn y corff dynol gan y genyn HLA-DMA yw HLA-DMA a elwir hefyd yn HLA class II histocompatibility antigen, DM alpha chain (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 6, band 6p21.32.

HLA-DMA
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1HDM, 2BC4, 4FQX, 4GBX
Dynodwyr
Cyfenwau	HLA-DMA, D6S222E, DMA, HLADM, RING6, major histocompatibility complex, class II, DM alpha
Dynodwyr allanol	OMIM: 142855 HomoloGene: 4464 GeneCards: HLA-DMA
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • MHC class II protein complex binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • integral component of membrane • cell surface • endosome • lysosome • extracellular exosome • late endosome membrane • bilen • lysosomal membrane • MHC class II protein complex • intracellular membrane-bounded organelle Prosesau biolegol • antigen processing and presentation of peptide or polysaccharide antigen via MHC class II • peptide antigen assembly with MHC class II protein complex • antigen processing and presentation • antigen processing and presentation of exogenous peptide antigen via MHC class II • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response • immune system process • adaptive immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3108	n/a
Ensembl	ENSG00000243215 ENSG00000243719 ENSG00000239463 ENSG00000204257 ENSG00000242361 ENSG00000241394 ENSG00000243189 ENSG00000242685	n/a
UniProt	P28067	n/a
RefSeq (mRNA)	NM_006120	n/a
RefSeq (protein)	n/a	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HLA-DMA.

• DMA
• HLADM
• RING6
• D6S222E

Llyfryddiaeth

• "HLA-DMA polymorphisms differentially affect MHC class II peptide loading. ". J Immunol. 2015. PMID 25505276.
• "Spatial separation of HLA-DM/HLA-DR interactions within MIIC and phagosome-induced immune escape. ". Immunity. 2005. PMID 15723810.
• "Increased expression of intracellular HLA-DM but not on the surface of blood monocyte-derived dendritic cells during maturation. ". Yonsei Med J. 2003. PMID 12728471.
• "In vivo and in vitro modulation of HLA-DM and HLA-DO is induced by B lymphocyte activation. ". J Immunol. 2001. PMID 11739502.
• "Sequence analysis of two novel HLA-DMA alleles.". Immunogenetics. 1994. PMID 8026867.