HSD17B11

Protein sy'n cael ei godio yn y corff dynol gan y genyn HSD17B11 yw HSD17B11 a elwir hefyd yn Hydroxysteroid 17-beta dehydrogenase 11 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 4, band 4q22.1.

HSD17B11
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1YB1
Dynodwyr
Cyfenwau	HSD17B11, 17-BETA-HSD11, 17-BETA-HSDXI, 17BHSD11, DHRS8, PAN1B, RETSDR2, SDR16C2, hydroxysteroid (17-beta) dehydrogenase 11, hydroxysteroid 17-beta dehydrogenase 11
Dynodwyr allanol	OMIM: 612831 HomoloGene: 69209 GeneCards: HSD17B11
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • oxidoreductase activity • steroid dehydrogenase activity • estradiol 17-beta-dehydrogenase activity Cydrannau o'r gell • cytoplasm • extracellular region • cytosol • lipid droplet Prosesau biolegol • estrogen biosynthetic process • androgen catabolic process • lipid metabolism • steroid biosynthetic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	51170	n/a
Ensembl	ENSG00000198189	n/a
UniProt	Q8NBQ5	n/a
RefSeq (mRNA)	NM_016245	n/a
RefSeq (protein)	NP_057329	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn HSD17B11.

• DHRS8
• PAN1B
• RETSDR2
• SDR16C2
• 17BHSD11
• 17-BETA-HSD11
• 17-BETA-HSDXI

Llyfryddiaeth

• "Cloning and expression of a novel tissue specific 17beta-hydroxysteroid dehydrogenase. ". Endocr Res. 1998. PMID 9888557.
• "Identification and characterization of the ER/lipid droplet-targeting sequence in 17beta-hydroxysteroid dehydrogenase type 11. ". Arch Biochem Biophys. 2008. PMID 18804447.
• "Human dehydrogenase/reductase (SDR family) member 8 (DHRS8): a description and evaluation of its biochemical properties. ". Mol Cell Biochem. 2016. PMID 26472732.
• "Transcriptional regulation of type 11 17β-hydroxysteroid dehydrogenase expression in prostate cancer cells. ". Mol Cell Endocrinol. 2011. PMID 21549806.
• "17beta-hydroxysteroid dehydrogenase type 11 (Pan1b) expression in human prostate cancer.". Neoplasma. 2009. PMID 19469652.