IGFBP2

Protein sy'n cael ei godio yn y corff dynol gan y genyn IGFBP2 yw IGFBP2 a elwir hefyd yn Insulin like growth factor binding protein 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q35.

IGFBP2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2H7T
Dynodwyr
Cyfenwau	IGFBP2, IBP2, IGF-BP53, insulin like growth factor binding protein 2
Dynodwyr allanol	OMIM: 146731 HomoloGene: 499 GeneCards: IGFBP2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • insulin-like growth factor binding • growth factor binding • insulin-like growth factor I binding • insulin-like growth factor II binding • GO:0001948, GO:0016582 protein binding • signaling receptor binding Cydrannau o'r gell • extracellular region • apical plasma membrane • extracellular exosome • GO:0016023 cytoplasmic vesicle • extracellular space Prosesau biolegol • response to estradiol • response to retinoic acid • response to nutrient • female pregnancy • response to steroid hormone • response to mechanical stimulus • GO:0010260 heneiddio • response to glucocorticoid • response to lithium ion • response to estrogen • regulation of insulin-like growth factor receptor signaling pathway • cellular response to hormone stimulus • regulation of cell growth • regulation of growth • negative regulation of canonical Wnt signaling pathway • GO:0072468 signal transduction • positive regulation of activated T cell proliferation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	3485	n/a
Ensembl	ENSG00000115457	n/a
UniProt	P18065	n/a
RefSeq (mRNA)	NM_001313990 NM_001313992 NM_001313993 NM_000597	n/a
RefSeq (protein)	NP_000588 NP_001300919 NP_001300921 NP_001300922	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn IGFBP2.

• IBP2
• IGF-BP53

Llyfryddiaeth

• "Preoperative serum levels of insulin-like growth factor-binding protein 2 predict prognosis of gastric cancer patients. ". Oncotarget. 2017. PMID 28036255.
• "Elevation of IGFBP2 contributes to mycotoxin T-2-induced chondrocyte injury and metabolism. ". Biochem Biophys Res Commun. 2016. PMID 27416762.
• "Insulin-Like Growth Factors (IGF) and IGF-Binding Proteins (IGFBP) in the Serum of Patients with Ovarian Tumors. ". Bull Exp Biol Med. 2016. PMID 27165066.
• "Insulin-like growth factor binding protein-2 regulates β-catenin signaling pathway in glioma cells and contributes to poor patient prognosis. ". Neuro Oncol. 2016. PMID 27044294.
• "Insulin-like growth factor binding protein-2 as a novel biomarker for disease activity and renal pathology changes in lupus nephritis.". Clin Exp Immunol. 2016. PMID 26616478.